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View Structure Prediction Details

Protein: CE30527
Organism: Caenorhabditis elegans
Length: 676 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE30527.

Description E-value Query
Range
Subject
Range
gi|7500397 - gi|7500397|pir||T32771 hypothetical protein F33D11.9b - Caenorhabditis elegans
633.0 [0..1] [676..263]

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Predicted Domain #1
Region A:
Residues: [1-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENLLKFTNK KLKLLEMALE ISKDGGTTRP KILDKILKFR KVALIIAYIG AYLSAQWLFD  60
   61 PVNMEVTRIS EHSLMPGLVT PKFDKSGIAI QLYRRFSDLP KSKSQQELIH TIFSDLGLEC 120
  121 FTHKWRSKVA GNPMNGENVY GFIRGPRNDG AEAQMIVVQL GRSEKSRRMM SRMLAFVDYA 180
  181 KDQVYWARDI VIVFVDGGEK NDSIEKAAFA LDAFLLKYQK IEALNSKKSI TVEADEIQAQ 240
  241 TGALIGGVVY DLSGMAVKGQ HIVNIQTNGL NGQQVNLDVF NGITKIADSK HHSRVAIFGT 300
  301 LHRHSNPYME YSPFIVPMRA LYTQAFISIE GIHSVLGKYG VQGLTVGLSH DYSEKQTGQF 360
  361 IEEVSRMLNN VLERLHQSYF MYVLADDLHF SSIAMYIIPL TILVSPLVIS A

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.03
Match: 1rtqA
Description: The 0.95 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.30073863026596 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.04545175523841 bayes_pls_golite062009
peptidase activity 0.700635398774672 bayes_pls_golite062009
binding 0.374473226792137 bayes_pls_golite062009
nucleic acid binding 0.362145256746391 bayes_pls_golite062009
protein binding 0.192842853386021 bayes_pls_golite062009
metallopeptidase activity 0.177551285129758 bayes_pls_golite062009
transcription regulator activity 0.171364523459 bayes_pls_golite062009
hydrolase activity 0.091850616360333 bayes_pls_golite062009
DNA binding 0.0535456396545306 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [412-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YFEWTKIQEF QFPVVHLAFH VLGFFYYIAT TYVFQTIGTT FVLQW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [457-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQWPFVGIDG CDGQFTPSWS LINSFLIFFM IPLGPYVFLK EPVRCVPSMR IVCLLETSLV  60
   61 LYGICLTNFG LAILCTAFVV PIVFLMTYES SDRTRSIFRS SVLAILNPIS VLAFVAINIP 120
  121 GMFGQLFPTI SQDSWLAAAQ SIALTAIRED VEFKVNHFFL LCCFGYPIWN MLFACSMRYG 180
  181 PEPQGSLGIF GNGSDDDDGD DDDGPQKTNR GHSTKKNKRE 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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