| Protein: | acr-19 |
| Organism: | Caenorhabditis elegans |
| Length: | 554 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-19.
| Description | E-value | Query Range |
Subject Range |
|
|
440.0 | [0..11] | [549..87] |
|
Region A: Residues: [1-216] |
1 11 21 31 41 51
| | | | | |
1 MRRRFEIGIA FFFALFRVIW TGDHERRLYA KLAENYNKLA RPVRNESEAV VVLLGMDYQQ 60
61 ILDIDEKHQI MNSNVWLRMS WTDHYLTWDP SEFGNIKEVR LPINNIWKPD VLLYNSVDQQ 120
121 FDSTWPVNAV VLYTGNVTWI PPAIIRSSCA IDIAYFPFDT QHCTMKFGSW TYSGFFTDLI 180
181 NTTISPATYK PNGEWELLGL TSQRSIFFYE CCPEPY
|
| Detection Method: |  |
| Confidence: | 79.69897 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [217-554] |
1 11 21 31 41 51
| | | | | |
1 YDVTFTVSIR RRTLYYGFNL LLPCMLISSL ALLSFTLPAD CGEKLNLGVT IFMSLCVFMI 60
61 MVAEAMPQTS DALPLIQIYF SCIMFQVGAS VVATVIALNF HHRSPEQYKP MNKFLKTLLL 120
121 GWLPTLLGME RPDVLELSVH GAHYASDNKK KQRQYLIEVE RHILTRPNGN GHSAVDKAVH 180
181 LDLSTGNPHS DAKKSSPSPK RTSASIMGMT GLPTTQMNGA LDSSINKYTC TKVTRPLENG 240
241 SATINHKSSP QINPINNNNI YKCANNQKTQ FEDRHFHHIL NELRVISARV RKEEAMHALQ 300
301 ADWMFASRVV DRVCFLAFSA FLFMCTAIIS YNAPHLFV
|
| Detection Method: | |
| Confidence: | 34.0 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetylcholine binding | 13.9752632471881 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 13.7533645836795 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 13.1511875247796 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 11.9525876011069 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| cation channel activity | 11.7442066737514 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| amine binding | 9.11982124959723 | bayes_pls_golite062009 |
| chloride channel regulator activity | 9.10587892909341 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 7.19173677417054 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.50066216027179 | bayes_pls_golite062009 |
| receptor activity | 4.29130501016821 | bayes_pls_golite062009 |
| neurotransmitter binding | 4.25797760547212 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 4.15404686068319 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| adenylate cyclase binding | 3.30190657223613 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.25766805801029 | bayes_pls_golite062009 |
| 1.68370717591127 | bayes_pls_golite062009 | |
| channel regulator activity | 1.66978990310631 | bayes_pls_golite062009 |
| protein binding | 1.45740893920165 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.53275410807921 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 0.417103731247281 | bayes_pls_golite062009 |
| kinase binding | 0.365355763029699 | bayes_pls_golite062009 |
| protein kinase binding | 0.350601457777817 | bayes_pls_golite062009 |
