| Protein: | acr-12 |
| Organism: | Caenorhabditis elegans |
| Length: | 573 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-12.
| Description | E-value | Query Range |
Subject Range |
|
|
451.0 | [0..9] | [573..1] |
|
Region A: Residues: [1-369] |
1 11 21 31 41 51
| | | | | |
1 MLYKKRLQMF SFNWALILLV AVGGTNAFKI KRTAKDLESQ LYEDLLFDYN KVPRPVKNSS 60
61 DILTVDVGAS LIRIIDVDEK NQVLTTNLWL EMKWNDAKLT WTPEKYGGLK TLHIPSDFIW 120
121 TPDLVLYNNA AGDPDITILT DALVTFEGNV YWQPPAIYKS FCPIDVTWFP YDSQKCEMKF 180
181 GTWTYTGRYV DLKQLPQEEV VTITKDDNDV EFMQQGMDLS FFYRSAEWDL LSLTSERHSV 240
241 LYASCCGPEK YVDITYYFGL RRKTLFFTCN LILPCFLISI LTTFVFYLSD HKITFSISIL 300
301 VTLTVFFLVL IDLMPPTSLV IPMFGRYLIT TMILVALSTV VSVITVNFRF RSGSAHKMSP 360
361 WIRAVFLKF
|
| Detection Method: |  |
| Confidence: | 79.0 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [370-573] |
1 11 21 31 41 51
| | | | | |
1 LPKILLMSRP EKGEVTKQPP LVNAASLVGS NYATAAKAAN EYRNKAKGKN NDLMSLRGKP 60
61 SSQAVLNNTF DMRMRNNDST VENRLKPYLC AQNNNAPTVA FRKTKRQKSK SVDDVVFMNL 120
121 LNQVRFIAEH FRHNELEGEI SDDWTFVAMV LDRLFLIIFS VLNVGTVFII LESPSLYDYS 180
181 KPMNITVPNK PLGQANFYSS WNLK
|
| Detection Method: | |
| Confidence: | 37.09691 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetylcholine binding | 13.9752632471881 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 13.7533645836795 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 13.1511875247796 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 11.9525876011069 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| cation channel activity | 11.7442066737514 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| amine binding | 9.11982124959723 | bayes_pls_golite062009 |
| chloride channel regulator activity | 9.10587892909341 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 7.19173677417054 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| neurotransmitter binding | 4.25797760547212 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 4.15404686068319 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| adenylate cyclase binding | 3.30190657223613 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.25766805801029 | bayes_pls_golite062009 |
| 1.68370717591127 | bayes_pls_golite062009 | |
| channel regulator activity | 1.66978990310631 | bayes_pls_golite062009 |
| protein binding | 1.45740893920165 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.42422063123689 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| kinase binding | 0.365355763029699 | bayes_pls_golite062009 |
| protein kinase binding | 0.350601457777817 | bayes_pls_golite062009 |
