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View Structure Prediction Details

Protein: CE28327
Organism: Caenorhabditis elegans
Length: 232 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE28327.

Description E-value Query
Range
Subject
Range
gi|106771275, gi... - gi|148655742|ref|YP_001275947.1| ATP-dependent protease La [Roseiflexus sp. RS-1], gi|148567852|gb|A...
147.0 [0..1] [137..673]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPEIERKSH LAYQVARFEA VAMGFPVQYR QVVVEFYYHG RLDGSSGTLA TAVGLLALFT  60
   61 GVEISPRFAI TGSLDVFGWP PYCCLFSKMS SGGGNQKSDG QVEEDAAECK FPKEFETTTC 120
  121 DALLTAEVYL LLEHRRQSSE SK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.154902
Match: 1rr9A
Description: Catalytic domain of E.coli Lon protease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleotidyltransferase activity 4.54967057318159 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 3.65740283278356 bayes_pls_golite062009
transferase activity 3.04205212257097 bayes_pls_golite062009
transcription regulator activity 2.31170537288595 bayes_pls_golite062009
3'-5'-exoribonuclease activity 2.16830676862423 bayes_pls_golite062009
RNA binding 2.05527376734941 bayes_pls_golite062009
binding 2.02349222243183 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.94887328847363 bayes_pls_golite062009
exoribonuclease activity 1.90081280972069 bayes_pls_golite062009
nucleic acid binding 1.7414193619112 bayes_pls_golite062009
DNA binding 1.58926319237456 bayes_pls_golite062009
structural constituent of ribosome 1.38725999901881 bayes_pls_golite062009
ribonuclease activity 1.31550811238109 bayes_pls_golite062009
mRNA binding 1.17402119891853 bayes_pls_golite062009
structural molecule activity 1.04534150109805 bayes_pls_golite062009
catalytic activity 0.878454819018611 bayes_pls_golite062009
nuclease activity 0.69721312877891 bayes_pls_golite062009
3'-5' exonuclease activity 0.477960254167 bayes_pls_golite062009
deacetylase activity 0.390237258762359 bayes_pls_golite062009
protein binding 0.214066724623027 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [143-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEIEEMSEVF IKTLNYARRM SRFKNRETIR AVRAIFSEKH LHKFEVAQIA NLCPENAEEA  60
   61 KALVPSLENK IEESELEEVL KDLQSKRTFQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.522879
Match: 2c35A
Description: Subunits Rpb4 and Rpb7 of human RNA polymerase II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-directed RNA polymerase activity 8.43501887532465 bayes_pls_golite062009
RNA polymerase activity 8.43501887532465 bayes_pls_golite062009
nucleotidyltransferase activity 5.88847066010291 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 3.86808684657182 bayes_pls_golite062009
transferase activity 3.42143089321218 bayes_pls_golite062009
transcription regulator activity 2.4721848902664 bayes_pls_golite062009
binding 2.44438550013082 bayes_pls_golite062009
catalytic activity 1.17990683373825 bayes_pls_golite062009
histone acetyltransferase activity 0.8583308140751 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.8583308140751 bayes_pls_golite062009
protein binding 0.520045897607933 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 0.430689791429257 bayes_pls_golite062009
ribonuclease activity 0.35631508447468 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.288686121121112 bayes_pls_golite062009
ribonuclease III activity 0.0092766021353235 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle