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View Structure Prediction Details

Protein: lin-29
Organism: Caenorhabditis elegans
Length: 459 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lin-29.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
660.0 [0..4] [458..2427]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQTVLDSAF NSPVDSGIAG TTTGSGSTTH FGVGTNFKVS VRSSSRSTDG TDSTDGANSD  60
   61 NVTGSTGSTP AHHSITNLNM ALSQHSIDSA TAASSTNPFP HFNQADLLNF HQNSLLPHHM 120
  121 FSQFGRYPQF EQKPDVGVLQ QQMQMREA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 1tf3A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.71642591026275 bayes_pls_golite062009
transcription regulator activity 3.66965352784412 bayes_pls_golite062009
DNA binding 3.60136746748155 bayes_pls_golite062009
transcription factor activity 2.54048357633122 bayes_pls_golite062009
binding 2.46754839887217 bayes_pls_golite062009
transcription repressor activity 2.40376744272574 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.29326096340736 bayes_pls_golite062009
chromatin binding 1.30140469366308 bayes_pls_golite062009
transcription activator activity 1.29100548621048 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.73552256979331 bayes_pls_golite062009
transcription factor binding 0.53246783159686 bayes_pls_golite062009
sequence-specific DNA binding 0.52093073106685 bayes_pls_golite062009
transcription corepressor activity 0.503526851907562 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [149-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPYKCTQCVK AFANSSYLSQ HMRIHLGIKP FGPCNYCGKK FTQLSHLQQH IRTHTGEKPY  60
   61 KCKFTGCDKA FSQLSNLQSH SRCHQTDKPF KCNSCYKCFT DEQSLLDHIP KHKESKHLKI 120
  121 HICPFCGKSY TQQTYLQKHM TKHAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 2gliA
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.71642591026275 bayes_pls_golite062009
transcription regulator activity 3.66965352784412 bayes_pls_golite062009
DNA binding 3.60136746748155 bayes_pls_golite062009
transcription factor activity 2.54048357633122 bayes_pls_golite062009
binding 2.46754839887217 bayes_pls_golite062009
transcription repressor activity 2.40376744272574 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.29326096340736 bayes_pls_golite062009
chromatin binding 1.30140469366308 bayes_pls_golite062009
transcription activator activity 1.29100548621048 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.73552256979331 bayes_pls_golite062009
transcription factor binding 0.53246783159686 bayes_pls_golite062009
sequence-specific DNA binding 0.52093073106685 bayes_pls_golite062009
transcription corepressor activity 0.503526851907562 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [294-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSKASNFGND VVPADPFDPS LLSWNPMQGM GDNAHDSSSF NISSLTDQFA ANTMIGSQST  60
   61 NYNPAFQNSA FSQLFNIRNN RYLSEYPTST KNGERAPGFN MITPLENIQR YNGSSSSATA 120
  121 VVTATGSAVV SSTPSSTSSS SAGSSSSQGG VFNPQSLINN MKNHSY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.522879
Match: 2i13A
Description: No description for 2i13A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle