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View Structure Prediction Details

Protein: sfa-1
Organism: Caenorhabditis elegans
Length: 699 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sfa-1.

Description E-value Query
Range
Subject
Range
gi|46110397, gi|... - gi|46110397|ref|XP_382256.1| hypothetical protein FG02080.1 [Gibberella zeae PH-1], gi|42546868|gb|E...
303.0 [0..131] [600..1133]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKTGGNTEP MPFIRKWGNE AGEDLGAAPS ATAAPPPALV VPTISSMSSG DNKSPSRSES  60
   61 VSDRKRDRSR SRDRDRKKDR KKKDRSRERD RERRSSRSRS RSPRDRDRER RRRRSRSPPP 120
  121 RRRSRSGGDR RRRER

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPPSMVPNSP QRVKEPVINP LIREDLAAAV ESGAVPVEAV QAGAVVALNP AKKERRSRWS  60
   61 TTKSFVPGMP TILPADLTED QRNAYLLQLE IEDATRKLRL ADFGVAEGRE RSPSPEPVYD 120
  121 ANGK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [260-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLNTREVRKR QELEQLRHEK IQALLKINPN FKPPADYRAP NIRLHDKVWI PQEQFPDLNF  60
   61 VGLLIGPRGN TLKSLEAETG AKIIIRGKGS IKEGKLTNRL GPMPGENEPL HAYVTGTDMN 120
  121 VIKKACEKIK QVIAEATALP DNNELRKLQL RELALLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.39794
Match: 1k1gA
Description: RNA splicing factor 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.28581120742478 bayes_pls_golite062009
RNA binding 4.07234389285213 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
mRNA binding 2.74771386314615 bayes_pls_golite062009
protein binding 2.21586499514642 bayes_pls_golite062009
transcription regulator activity 2.01194399592256 bayes_pls_golite062009
DNA binding 1.78469836520678 bayes_pls_golite062009
transcription factor activity 0.866815968834173 bayes_pls_golite062009
0.649281624091344 bayes_pls_golite062009
structure-specific DNA binding 0.64468203163713 bayes_pls_golite062009
transcription repressor activity 0.594072241231183 bayes_pls_golite062009
single-stranded DNA binding 0.28490151670131 bayes_pls_golite062009
transcription activator activity 0.210494225017032 bayes_pls_golite062009
transcription factor binding 0.139588254197875 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [417-509]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTFRPEDLAN GARCSNCGSD EHKSWECPDA PNVTNQIKCT NCGAFGHISK DCKNPKGMYA  60
   61 SEAGMDDEYS ALMAELGETP AAGAGAGGGG GGH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.05
Match: 2ihxA
Description: No description for 2ihxA was found.

Predicted Domain #5
Region A:
Residues: [510-699]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VASAGGGISA MTGAGGEAPG GGAGGRGGGA HGGAGRGGGY QGGRGGGRGF QNPRDLFGPP  60
   61 KGEEEQQQQA NASMQHGYYD HYQQYAYPNQ YQQPYGAPAP PGGSAYGHQQ QQQQQQQQDY 120
  121 SDFYTSPGAR GGAGAKANKG WYGSGGGSSM PMPVPPPGGL GGFMPPPPPP PPMPGDLSSL 180
  181 LAAAPPPPPS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1y0fB
Description: No description for 1y0fB was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle