| Protein: | nhr-91 |
| Organism: | Caenorhabditis elegans |
| Length: | 474 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-91.
| Description | E-value | Query Range |
Subject Range |
|
|
299.0 | [0..1] | [474..7] |
|
Region A: Residues: [1-96] |
1 11 21 31 41 51
| | | | | |
1 MDVADSTSET PPVFDHDNLA LAAQTNLLQF YLTHLASTLV PPMKLDMRDS MTPSFSQTES 60
61 PNSETDDSTS AANKVLFSIL GTPTTDSTSN AVSKSS
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [97-187] |
1 11 21 31 41 51
| | | | | |
1 SKLCSVCGDK STGLHYGAAT CEGCKGFFKR SVQNKKVYHC SQDNCCEIDK QNRNRCQSCR 60
61 FRKCISKGML TEAVREDRMP GGRNGNSIYS N
|
| Detection Method: | |
| Confidence: | 21.39794 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [188-474] |
1 11 21 31 41 51
| | | | | |
1 YKQRRSIIRK TKDYVEEQER RPFQSLPSGK KLIKELVEMD CLDRLINLKG LRINPSANCD 60
61 IAPACKRLTR IGDEIVEQLV EWTKTLPFFD ELPVEAHTHL LTQRWAELVL LSAGYYACSV 120
121 FTPDSPDTTE MIDETDEISF TNPQVNLRLL QNRLSLVLGK EIPLEHVAKE AGPLVTRFTT 180
181 LLHSFSNLKV SPEAYVCIKA ITLLHLSADS TLDRSIIDKV NTLQDHFVKT LQIHLHQPGE 240
241 DAQTTSLAQI LDWLPDLRNA SSVLLHSKMF YVPFLLCKNP RRLVFDE
|
| Detection Method: | |
| Confidence: | 36.30103 |
| Match: | 1xdkB |
| Description: | Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| transcription activator activity | 3.20381581407476 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.01488410150634 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| protein binding | 2.16479360297106 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 0.72116377387566 | bayes_pls_golite062009 |
| promoter binding | 0.58091332905515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.48550016963446 | bayes_pls_golite062009 |
| hormone receptor binding | 0.46017130739564 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1337430602389 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
