| Protein: | nhr-34 |
| Organism: | Caenorhabditis elegans |
| Length: | 499 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-34.
| Description | E-value | Query Range |
Subject Range |
|
|
310.0 | [0..1] | [499..11] |
|
Region A: Residues: [1-118] |
1 11 21 31 41 51
| | | | | |
1 MAESKFSILK GEEFTGLKCR VCGDSRAGRH YGTIACNGCK GFFRRSIWEQ RDYVCRFGGK 60
61 CLVVQEYRNR CRACRLRKCF TVGMDARAVQ SERDKHKKNP KDSNNEGSTS PQYPTAST
|
| Detection Method: |  |
| Confidence: | 25.69897 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [119-499] |
1 11 21 31 41 51
| | | | | |
1 PISIPSTSTS QTPTSSVNSY NFQNIPGIVS RSFSENLIMR DNSVPVMETS QSAALSHVPL 60
61 VRYLIDLEKA TDNLIDENCD FMSMEFDQLC RVDVTIEAAF RQPGVVAKRT PPRWLALERL 120
121 TTLEDVHIAW CRSFVLCIDY AKIMKDYQEL SPTDQFTLLR NRVISVNWLC HTYKTFKAGC 180
181 DGVALVNGSW YPRDKELQKQ LDPGCNHYFR ILSEHLMEDL VIPMREMDMD EGEFVILKAL 240
241 ILFRAHRRLS EEGRAHIKRV RDKYIEALYQ HVQHQHRHFS SVQTSMRISK ILLLLPSIEH 300
301 LSQQEDDNVQ FLALFNLANL NGLPYELHSS IKQHIPNGDD SDDTQVNEVT SNNDGPRSSE 360
361 SSHTPQSVST SQFLEFKPSL H
|
| Detection Method: | |
| Confidence: | 44.69897 |
| Match: | 1xdkB |
| Description: | Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| vitamin D3 receptor activity | 5.5563493713822 | bayes_pls_golite062009 |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 4.81441024181511 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 4.66615836207965 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 3.91470119037087 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| hormone receptor binding | 3.79647267365529 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator activity | 3.20381581407476 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.01488410150634 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| vitamin D binding | 2.05947211013242 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.56146647486761 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.48246587604476 | bayes_pls_golite062009 |
| estrogen receptor activity | 1.47290778095383 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| promoter binding | 1.16363620574097 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| juvenile hormone binding | 0.814202236506491 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.754240851368212 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
| estrogen response element binding | 4.73336420190096E-4 | bayes_pls_golite062009 |
