| Protein: | nhr-62 |
| Organism: | Caenorhabditis elegans |
| Length: | 515 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-62.
| Description | E-value | Query Range |
Subject Range |
|
|
316.0 | [0..2] | [514..351] |
|
Region A: Residues: [1-93] |
1 11 21 31 41 51
| | | | | |
1 MFSTLSPSAI DDILRHAVHF GQGTTAIAPS PVTFISTTTQ QSLGATYPGV FNPTTPTFNH 60
61 YQHQALPVTM HTSTSSAHHT TTGHGRGRRK NST
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [94-200] |
1 11 21 31 41 51
| | | | | |
1 INLVCVVCGD QAFGKHYGVN ACNGCKGFFR RSVWHNRQYL CRFEGRCAIA KEHRNVCRAC 60
61 RLKQCFVAGM NPRAVQSERV EREQNGSPNQ IEEDDYKDLS SPDTCSV
|
| Detection Method: | |
| Confidence: | 21.221849 |
| Match: | 2hanB |
| Description: | No description for 2hanB was found. |
| Term | Confidence | Notes |
| transcription regulator activity | 4.00967542385368 | bayes_pls_golite062009 |
| DNA binding | 3.60745514727532 | bayes_pls_golite062009 |
| nucleic acid binding | 3.47256374293954 | bayes_pls_golite062009 |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription activator activity | 2.9532663930699 | bayes_pls_golite062009 |
| transcription factor activity | 2.90769972671972 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.72967350701574 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.55186574506963 | bayes_pls_golite062009 |
| protein binding | 2.44501340584871 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.40923942043513 | bayes_pls_golite062009 |
| transcription repressor activity | 1.88834375049208 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.49515149729803 | bayes_pls_golite062009 |
| transcription factor binding | 1.38523780690867 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.26452462867497 | bayes_pls_golite062009 |
| transporter activity | 0.768214707487563 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.644659911825478 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.61572149323953 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.58115018700114 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.50876329665586 | bayes_pls_golite062009 |
| structural molecule activity | 0.441960874303873 | bayes_pls_golite062009 |
| receptor activity | 0.230063209127305 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.187612502757984 | bayes_pls_golite062009 |
| catalytic activity | 0.101795606736461 | bayes_pls_golite062009 |
|
Region A: Residues: [201-515] |
1 11 21 31 41 51
| | | | | |
1 EIQTDVDEQK PSSNNSAPLP SMELEMAKLS EQIVEMHRAV CSYVDPVTKR ENFDMKMETE 60
61 TTKIAFMNAF YNPEMIGPRT PLDITGRRVA TVKDVMDEWK RNFVLFSDWL RALPEYNQMS 120
121 IEDQIVLAKN RYGTFHWWMC ANWTVQAGCE GVCYSNGAYF PKQPEAQCIP DVKGSSGRMY 180
181 DSLSIPIKEL NLDETEIVLM LAVIIFSDEI TELADLTPAG KEHVRMVGNR FVRMLHHHVN 240
241 SKEYGEAMEN GDDTQNSSES QAAVRIAKMM ILLSATTNLV YLTSDNIQLM EVLHVVPSEY 300
301 LCHEVQFIQN SYETP
|
| Detection Method: | |
| Confidence: | 47.69897 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator binding | 2.98235973123409 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 2.64097559984752 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 2.30195937604451 | bayes_pls_golite062009 |
| transcription coactivator activity | 2.27959329058894 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| retinoid binding | 1.85307563045749 | bayes_pls_golite062009 |
| prostacyclin receptor activity | 1.74944518684208 | bayes_pls_golite062009 |
| isoprenoid binding | 1.73854742753963 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.60419100774741 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| promoter binding | 1.28787959668198 | bayes_pls_golite062009 |
| palmitoyl-CoA hydrolase activity | 1.23181585568439 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| hormone receptor binding | 0.95284349923679 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.47826452126899 | bayes_pls_golite062009 |
| lipid binding | 0.475303782949439 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.42652610679613 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
