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View Structure Prediction Details

Protein: fzy-1
Organism: Caenorhabditis elegans
Length: 507 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fzy-1.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
558.0 [0..1] [504..1230]

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Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNKGRTPGS AGRTVRSSAQ QNGLTMRKRD MTPTRNTNLL PNATFVGDRF LGVRLDQDEL  60
   61 DHANHLMTSK LYSNKENLNN SMSEPNSPEK KSVEGEALKQ MMRHKSTGAL TDADDGDRIL 120
  121 CYKKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [126-507]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAPPPAIGYI NQAKVLYSTN SVINPASSVK KSTRHVKETA TKVLDGPGLT KDLYSRHLDW  60
   61 GCHNWVAVAL GHELYLWNTE TCVIKNLFED NAPTNEGLIT SVRWSQEGRY ISLGYASGAV 120
  121 KIYDPNRPKT TEYVRELRTL RVGGASRCAS IAWRKQGVMT CGYKSGDIVN HDVRISQHVV 180
  181 SSWGGDNGHC RDVTALEWSA DENMCVSGSS DRTAKIWDGR HVRGSTVIQD PEPMFTIDEH 240
  241 TGQVRTAQFC SFRDGILATG GGINDGTVKL WDVKRQFQKV RELNVCETGG VGGIVFNRPY 300
  301 SEMLTASDDG FLRIYRFNAN YKLSHEIQAS NEPIMDLVGS PFDEVLIGDM EETLKVFQLF 360
  361 NVDKSTNILD RTAPKNVGLN VR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.69897
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.42570478946173 bayes_pls_golite062009
cytoskeletal protein binding 2.20122168933317 bayes_pls_golite062009
dynein binding 1.70203790763669 bayes_pls_golite062009
nucleic acid binding 1.63776917287392 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.59258100795958 bayes_pls_golite062009
transcription regulator activity 1.56901113625383 bayes_pls_golite062009
small conjugating protein ligase activity 1.48624129577934 bayes_pls_golite062009
actin binding 1.40054662654509 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
tubulin binding 1.10875870970504 bayes_pls_golite062009
DNA binding 1.0776875611211 bayes_pls_golite062009
microtubule binding 1.03769395387791 bayes_pls_golite062009
transporter activity 0.692270256454453 bayes_pls_golite062009
transcription factor activity 0.541665384827041 bayes_pls_golite062009
acid-amino acid ligase activity 0.535041400676017 bayes_pls_golite062009
transcription repressor activity 0.371091121886939 bayes_pls_golite062009
structural molecule activity 0.254012051644049 bayes_pls_golite062009
transcription factor binding 0.244641056034795 bayes_pls_golite062009
hydrolase activity 0.181211933860468 bayes_pls_golite062009
substrate-specific transporter activity 0.121183207943714 bayes_pls_golite062009
transcription cofactor activity 0.0160791658499004 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle