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View Structure Prediction Details

Protein: exl-1
Organism: Caenorhabditis elegans
Length: 238 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for exl-1.

Description E-value Query
Range
Subject
Range
gi|93354450, gi|... - gi|94310598|ref|YP_583808.1| glutathione S-transferase-like protein [Ralstonia metallidurans CH34], ...
166.0 [0..9] [238..49]

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Predicted Domain #1
Region A:
Residues: [1-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTFSLWLPA GSNNVHPCGD PYAHHLFMRC LYHAKHDPTM KFDVKTTNVN KTSQEFKNTG  60
   61 LRRMPGISAE ESGETQTFET EDDILDFLEY LKPERGDDEE AENATCDLFR QFARFVKDVE 120
  121 HRDTAFNTEL LRLDKYLSEQ ETKFLISDDV THIDCLVLTR LHSIRVAAKM LKNYEIPADL 180
  181 SHVLDYLKAG YATEMFRVSC PSDQEIVLHW TELKDTPRLS AKDRAKLVRE EPVFSFSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.39794
Match: 1rk4A
Description: Crystal Structure of a Soluble Dimeric Form of Oxidised CLIC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
anion channel activity 3.43309717940669 bayes_pls_golite062009
chloride channel activity 3.43309717940669 bayes_pls_golite062009
anion transmembrane transporter activity 2.95357085969061 bayes_pls_golite062009
ion transmembrane transporter activity 2.80355375991545 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.57358006453916 bayes_pls_golite062009
ion channel activity 1.93467867578363 bayes_pls_golite062009
substrate-specific channel activity 1.85548385190106 bayes_pls_golite062009
passive transmembrane transporter activity 1.85004112385169 bayes_pls_golite062009
channel activity 1.85004112385169 bayes_pls_golite062009
voltage-gated chloride channel activity 1.53793640572798 bayes_pls_golite062009
voltage-gated anion channel activity 1.53793640572798 bayes_pls_golite062009
molecular transducer activity 1.48840493532061 bayes_pls_golite062009
signal transducer activity 1.48840493532061 bayes_pls_golite062009
transporter activity 1.27462890839069 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
transmembrane transporter activity 1.07599729927609 bayes_pls_golite062009
gated channel activity 1.02378767677496 bayes_pls_golite062009
substrate-specific transporter activity 0.861215137904704 bayes_pls_golite062009
voltage-gated ion channel activity 0.677675994999412 bayes_pls_golite062009
voltage-gated channel activity 0.661169709002081 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 0.659499362710003 bayes_pls_golite062009
protein disulfide isomerase activity 0.659499362710003 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 0.536401864923239 bayes_pls_golite062009
transcription regulator activity 0.52671047749426 bayes_pls_golite062009
nucleic acid binding 0.32476916216195 bayes_pls_golite062009
DNA binding 0.278017923256183 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009
transcription repressor activity 0.00678211696545472 bayes_pls_golite062009

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