| Protein: | acr-6 |
| Organism: | Caenorhabditis elegans |
| Length: | 562 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-6.
| Description | E-value | Query Range |
Subject Range |
|
|
434.0 | [0..7] | [559..25] |
|
Region A: Residues: [1-349] |
1 11 21 31 41 51
| | | | | |
1 MRSLKKPAQS TQVPPAYNKI AFPSGEFNNT LTIEFKLRLD QIVDVHEKDQ VITLKGTLIH 60
61 HWLDYRLSWN PDEFGNITLM HFPGEMLWLP DIILYNNAHG SPWVSETTQV HVSFEGRVTW 120
121 QPPVVYDAFC NIDIEWYPYD LQICELKFGS WTYGGSQLNL IHLTTDQANE STDATGDNVW 180
181 KVERGVDLSN YQESVEWDLL SVEGIRHKKW YPCCDYPSID ITYYLHIRRK KLFYTVNMII 240
241 PCVCLASMTL WVTSKFLSKF VFGRGLIVFY LPCESHQKIQ LCISVLVALT LYFLMLIDII 300
301 PPTSIVTPLI LKYLSFTMIM VALSVTCTVF VSFYNFLKMI QNIHYRAYY
|
| Detection Method: |  |
| Confidence: | 78.69897 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [350-562] |
1 11 21 31 41 51
| | | | | |
1 QPMPRFVKHW FIEKLGKKLL ISRKTEQAQY HRTAQHVKQV NALSAMNILE KQFQKTLFEL 60
61 EIATMAKKTV TAAPKTVNSI FLELPMMNRS VSVKIRKPSV KAVKNRMRRL LSIDMTDDIR 120
121 GKETEEISPE TTKDTDPDRE KLRKAEKNIH FIAKTLTDER RAQEAEADWQ FVSLVIDRML 180
181 LIIFSFTITI GTILTIFSAP TMRDNREPIA INP
|
| Detection Method: | |
| Confidence: | 37.30103 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetylcholine binding | 13.9752632471881 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 13.7533645836795 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 13.1511875247796 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 11.9525876011069 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| cation channel activity | 11.7442066737514 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| amine binding | 9.11982124959723 | bayes_pls_golite062009 |
| chloride channel regulator activity | 9.10587892909341 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 7.19173677417054 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| neurotransmitter binding | 4.25797760547212 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 4.15404686068319 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| adenylate cyclase binding | 3.30190657223613 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.25766805801029 | bayes_pls_golite062009 |
| 1.68370717591127 | bayes_pls_golite062009 | |
| channel regulator activity | 1.66978990310631 | bayes_pls_golite062009 |
| protein binding | 1.45740893920165 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.42422063123689 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| kinase binding | 0.365355763029699 | bayes_pls_golite062009 |
| protein kinase binding | 0.350601457777817 | bayes_pls_golite062009 |
