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View Structure Prediction Details

Protein: rpb-7
Organism: Caenorhabditis elegans
Length: 197 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpb-7.

Description E-value Query
Range
Subject
Range
gi|78701235, gi|... - gi|78701235|ref|ZP_00865687.1| Polyribonucleotide nucleotidyltransferase [Alkalilimnicola ehrlichei ...
168.0 [0..3] [191..534]

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Predicted Domain #1
Region A:
Residues: [1-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQGRLLAHS SSRWHATGAL TLRMFFHLSL DHEVCLHPKY FGPNLNETIK MKLFNEVEGT  60
   61 CTGKYGFVIA VTTIDTIGHG LIQPGRGFVI YPVRYKAIVF RPFKGQVVDG VVTQVNKVGI 120
  121 FCDIGPLSCF ISRHCIPPDM EFDPNSEKPC YKTNDEANVI RNDDEIRVKL IGTRVDANDI 180
  181 FAIGTLMDDF LGLCQAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.69897
Match: 2c35B
Description: Subunits Rpb4 and Rpb7 of human RNA polymerase II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-directed RNA polymerase activity 5.58573473432218 bayes_pls_golite062009
RNA polymerase activity 5.58573473432218 bayes_pls_golite062009
structural constituent of ribosome 5.1118741250402 bayes_pls_golite062009
structural molecule activity 4.51553901145182 bayes_pls_golite062009
nucleic acid binding 4.29626483284963 bayes_pls_golite062009
RNA binding 3.99161318590718 bayes_pls_golite062009
ribonuclease activity 3.83159232224897 bayes_pls_golite062009
DNA binding 3.53568546959418 bayes_pls_golite062009
nucleotidyltransferase activity 3.34659726705133 bayes_pls_golite062009
binding 2.83465364476231 bayes_pls_golite062009
2.80746531284205 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.58106651553389 bayes_pls_golite062009
exoribonuclease activity 2.41262897171619 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 2.38378389593693 bayes_pls_golite062009
transcription regulator activity 2.10110937001387 bayes_pls_golite062009
transferase activity 2.03373182784225 bayes_pls_golite062009
structure-specific DNA binding 1.81524862921454 bayes_pls_golite062009
mRNA binding 1.660993824641 bayes_pls_golite062009
single-stranded DNA binding 1.62996999055328 bayes_pls_golite062009
translation regulator activity 1.46320772716954 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.40718318783582 bayes_pls_golite062009
translation initiation factor activity 1.27539679024898 bayes_pls_golite062009
protein binding 1.20309946451799 bayes_pls_golite062009
transcription activator activity 1.09079153283893 bayes_pls_golite062009
transcription factor activity 0.937752547283357 bayes_pls_golite062009
sequence-specific DNA binding 0.85691075793641 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.83268201349295 bayes_pls_golite062009
hydrolase activity 0.724860465280978 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.583085644017496 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 0.474251377131502 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 0.47336621289748 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 0.47336621289748 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.223941674251642 bayes_pls_golite062009

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