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View Structure Prediction Details

Protein: CE20297
Organism: Caenorhabditis elegans
Length: 404 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE20297.

Description E-value Query
Range
Subject
Range
gi|149021017, gi... - ref|XP_341555.1| similar to Kin protein [Rattus norvegicus], gi|157817336|ref|NP_001102999.1| antige...
441.0 [0..1] [404..1]

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Predicted Domain #1
Region A:
Residues: [1-60]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKHEKGSSK DLANRTKSKG LQKLKFFCQM CQKQCRDANG FKCHLTSEAH QRQLLLFAEN  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.25
Match: 1zu1A
Description: Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.3313734687716 bayes_pls_golite062009
DNA binding 3.15523680513517 bayes_pls_golite062009
transcription regulator activity 3.13450410278168 bayes_pls_golite062009
binding 2.79894364685962 bayes_pls_golite062009
transcription factor activity 2.20435466497656 bayes_pls_golite062009
structure-specific DNA binding 1.75169697620651 bayes_pls_golite062009
double-stranded DNA binding 1.44934603674695 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.39128012329158 bayes_pls_golite062009
transcription activator activity 1.29160378137114 bayes_pls_golite062009
protein binding 0.852654490075478 bayes_pls_golite062009
transcription repressor activity 0.772384703325109 bayes_pls_golite062009
sequence-specific DNA binding 0.628218277487796 bayes_pls_golite062009
transcription factor binding 0.565898381175308 bayes_pls_golite062009
chromatin binding 0.530600410029043 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.0453997626048568 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [61-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSYLRQFSN DFEKNFMQLL RTSYGTKRVR ANEVYNAFIK DKGHVHMNST VWHSLTGFVQ  60
   61 YLGSSGKCKI DEGD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [135-347]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGWYIAYIDQ EALIRKEEDQ RKQQQEKDDE ERHMQIMDGM VQRGKELAGD DEHEYEATEL  60
   61 IRDTPDQKIQ LDLNLGILDR KLDVKSGVAS AKISIFDMPK VKKEDPDEPG PSQPSRKSGK 120
  121 KRSRSRSPAA KKFSKKSALD EIKEMEERKK ERKNRKDYWM REGIVVKVIT KSLGSEYYKA 180
  181 KGVVRKVVDD YTAQVKLDDG TVVKLDQEHV ETV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [348-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPSLGRQMMI VNGAYRGQEA TLESIDEKRF SLRLKIASGP TRGRQIDVPY EDASKLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.522879
Match: 2ckkA
Description: No description for 2ckkA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle