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View Structure Prediction Details

Protein: CE19037
Organism: Caenorhabditis elegans
Length: 371 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE19037.

Description E-value Query
Range
Subject
Range
DHPS - deoxyhypusine synthase
gi|190689417, gi... - gi|190690779|gb|ACE87164.1| deoxyhypusine synthase protein [synthetic construct], gi|190689417|gb|AC...
568.0 [0..5] [371..2]

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Predicted Domain #1
Region A:
Residues: [1-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTNEAAASQ EDIALAQGAV LVKSCQVPDG SIPIRGFDFS TASGPDFSLS AILSSYMSTG  60
   61 FQATHLAQAI QQVNQMLSLR DTPLTCDDDE KLFPYPEGRQ KRSCTIFLGY TSNLVTSGLR 120
  121 EVLRYCVQRN LVDCIVTSAG GIEEDLIKCL KPSYLGTFTM DGAKLRSNGM NRAGNVLIPN 180
  181 DNYCAFEDWL MPILDECLVE QEEKHLNWTP SKLIQRLGER IGDESSILYW AAKHRIPVFC 240
  241 PALTDGSLGD MLYFHSVKSS PGLRVDIVED VRHINTIAVK SFKTGSIILG GGVVKHHINN 300
  301 ANLMRNGADH TVYINTGQEF DGSDSGAQPD EAVSWGKVKP SAGAVKVHAE ATLVFPLLVA 360
  361 ETFAKHEGHK D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 162.0
Match: 1rlzA
Description: Deoxyhypusine synthase holoenzyme in its high ionic strength, low pH crystal form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
deoxyhypusine synthase activity 4.8590235726137 bayes_pls_golite062009
transcription regulator activity 2.51117258094456 bayes_pls_golite062009
protein deacetylase activity 2.11398191156761 bayes_pls_golite062009
DNA binding 2.09930834951157 bayes_pls_golite062009
histone deacetylase activity 2.08718650273166 bayes_pls_golite062009
binding 2.06552694538163 bayes_pls_golite062009
nucleic acid binding 2.00972611627502 bayes_pls_golite062009
NAD-dependent protein deacetylase activity 1.93141177609772 bayes_pls_golite062009
NAD-dependent histone deacetylase activity 1.93141177609772 bayes_pls_golite062009
protein binding 1.52593340148652 bayes_pls_golite062009
deacetylase activity 1.15111805612466 bayes_pls_golite062009
transcription factor binding 1.07103864164531 bayes_pls_golite062009
transcription factor activity 1.0180828203704 bayes_pls_golite062009
catalytic activity 0.739210399081789 bayes_pls_golite062009
transcription repressor activity 0.516307124442946 bayes_pls_golite062009
transferase activity 0.483523935618287 bayes_pls_golite062009
transcription cofactor activity 0.42635585193838 bayes_pls_golite062009
transcription corepressor activity 0.23414654967509 bayes_pls_golite062009
hydrolase activity 0.169696911903799 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle