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View Structure Prediction Details

Protein: end-3
Organism: Caenorhabditis elegans
Length: 242 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for end-3.

Description E-value Query
Range
Subject
Range
gi|603164 - gi|603164|gb|AAA67886.1| BmGATA beta isoform 1
134.0 [0..117] [238..68]
gi|47223008 - gi|47223008|emb|CAG07095.1| unnamed protein product [Tetraodon nigroviridis]
134.0 [0..52] [239..14]
gi|8648977 - gi|8648977|emb|CAB94842.1| GATA-4 zinc-finger transcription factor [Oryctolagus cuniculus]
131.0 [0..117] [234..1]
gi|7381420 - gi|7381420|gb|AAF61481.1|AF184154_1 zinc finger DNA binding protein pannier [Ceratitis capitata]
130.0 [0..17] [238..2]
gi|477758 - gi|477758|pir||B48099 transcription factor GATA-2, retinoic acid-inducible - mouse (fragment)
129.0 [0..119] [228..1]
gi|3702858 - gi|3702858|gb|AAC62961.1| GATA transcription factor [Strongylocentrotus purpuratus]
127.0 [0..120] [236..1]
gi|6524988, gi|1... - gi|6524988|gb|AAF15275.1|AF191577_1 zinc finger transcription factor Gata4 [Danio rerio], gi|1885873...
122.0 [0..4] [241..51]

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Predicted Domain #1
Region A:
Residues: [1-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSNSFSSSS SSSNSPMSFD FGFPQFPEQV QFNEEGYGTP SPDVLQNMNY HHYPAQDMTT  60
   61 NSYNGGYDNS MQQNFMQPDN GAGYYNENYQ QMPDFQFPVQ NFDFTNQFEF TTPINDLQQS 120
  121 QTSINHTNPD NNENSMPEIP IDGGFNFFPA QEVQEWKPAR KASKNKIK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [169-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KISTMHINSS CSNCGCRETK LWRRNEQGET ECNPCNLYER VKGHKRPQHL WNKPAAKRRR  60
   61 RPVAPLVDSN AFNF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.30103
Match: 2gatA
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.52732993750126 bayes_pls_golite062009
transcription regulator activity 1.70015379754395 bayes_pls_golite062009
DNA binding 1.65515523003574 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.50367193346192 bayes_pls_golite062009
protein binding 1.41749048987708 bayes_pls_golite062009
transcription factor activity 1.14669021380366 bayes_pls_golite062009
sequence-specific DNA binding 1.0340476173844 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.01141398682075 bayes_pls_golite062009
nucleic acid binding 0.894860415786407 bayes_pls_golite062009
transcription activator activity 0.6614529953701 bayes_pls_golite062009
transcription factor binding 0.20735798780397 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.10722537662857 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle