YRC Public Data Repository - Protein Structure Prediction

Protein:	CE09074
Organism:	Caenorhabditis elegans
Length:	160 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE09074.

Description	E-value	Query Range	Subject Range
gi\|20807038 - gi\|20807038\|ref\|NP_622209.1\| Acetyltransferase [Thermoanaerobacter tengcongensis MB4] gi\|20807038, gi\|... - gi\|20807038\|ref\|NP_622209.1\| acetyltransferase [Thermoanaerobacter tengcongensis MB4], gi\|20515525\|g...	126.0	[0..1]	[155..1]
gi\|83648093, gi\|... - gi\|83648093\|ref\|YP_436528.1\| histone acetyltransferase HPA2-like acetyltransferase [Hahella chejuens...	122.0	[0..1]	[159..1]
gi\|109113135, gi... - gi\|109113135\|ref\|XP_001110296.1\| PREDICTED: similar to polyamine N-acetyltransferase isoform 2 [Maca...	120.0	[0..1]	[160..1]
gi\|187021159, gi... - gi\|39592072\|emb\|CAE75292.1\| Hypothetical protein CBG23260 [Caenorhabditis briggsae], gi\|187021159\|em... gi\|157762746 - gi\|157762746\|ref\|XP_001673715.1\| Hypothetical protein CBG23260 [Caenorhabditis briggsae AF16]	120.0	[0..1]	[160..369]
SAT2 - spermidine/spermine N1-acetyltransferase family member 2	118.0	[0..1]	[160..1]
gi\|146295284, gi... - gi\|82500547\|ref\|ZP_00885956.1\| Ribosomal-protein-alanine acetyltransferase [Caldicellulosiruptor sac...	118.0	[0..5]	[155..6]
gi\|114666211 - gi\|114666211\|ref\|XP_511959.2\| PREDICTED: polyamine N-acetyltransferase isoform 2 [Pan troglodytes]	118.0	[0..1]	[160..1]
gi\|57086379 - gi\|57086379\|ref\|XP_536624.1\| PREDICTED: similar to polyamine N-acetyltransferase [Canis familiaris]	118.0	[0..1]	[160..6]
gi\|167039151, gi... - gi\|167039151\|ref\|YP_001662136.1\| ribosomal-protein-alanine acetyltransferase [Thermoanaerobacter sp.... gi\|76797381, gi\|... - gi\|76797381\|ref\|ZP_00779704.1\| Ribosomal-protein-alanine acetyltransferase [Thermoanaerobacter ethan... gi\|241884906, gi... - gi\|241902652\|ref\|ZP_04787384.1\| ribosomal-protein-alanine acetyltransferase [Thermoanaerobacter broc... gi\|242230040, gi... - gi\|242258437\|ref\|ZP_04803241.1\| ribosomal-protein-alanine acetyltransferase [Thermoanaerobacter sp. ...	118.0	[0..3]	[155..2]
gi\|62424656 - gi\|62424656\|ref\|ZP_00379799.1\| COG0454: Histone acetyltransferase HPA2 and related acetyltransferase...	117.0	[0..4]	[160..1]

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Predicted Domain #1

Region A:
Residues: [1-160]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNFEIVTVT PDHAEQLISM IHELAEFEKM KSSVVNTAEK LRKDIENKAV HGFIAFIGEE  60
   61 PAGMNLFYYA YSTWVGQYLH MEDLYIRPQF RRMGLARTLW KKLAELARDK GIVRLEWAVL 120
  121 DWNKNAIALY DTVDYVNLTK SEGWFTFRMD GAAINKFADE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.30103
Match:	2beiA
Description:	X-ray structure of thialysine n-acetyltransferase (SSAT2) from homo sapiens
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
diamine N-acetyltransferase activity	2.43372305799009	bayes_pls_golite062009
transferase activity	2.42798083712145	bayes_pls_golite062009
N-acyltransferase activity	2.34015546109271	bayes_pls_golite062009
spermidine binding	1.99599610494414	bayes_pls_golite062009
catalytic activity	1.97933499002461	bayes_pls_golite062009
N-acetyltransferase activity	1.48038364316264	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.42711272311757	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	1.24328242407788	bayes_pls_golite062009
acyltransferase activity	1.2338745976101	bayes_pls_golite062009
binding	1.22537494136129	bayes_pls_golite062009
acetyltransferase activity	0.823367673029436	bayes_pls_golite062009
histone acetyltransferase activity	0.78221517928533	bayes_pls_golite062009
lysine N-acetyltransferase activity	0.78221517928533	bayes_pls_golite062009
ornithine decarboxylase regulator activity	0.498400437550611	bayes_pls_golite062009
transcription regulator activity	0.466327780973785	bayes_pls_golite062009
ornithine decarboxylase inhibitor activity	0.450278366782129	bayes_pls_golite062009
nucleic acid binding	0.398459895679745	bayes_pls_golite062009
transcription factor binding	0.18247998052007	bayes_pls_golite062009
protein binding	0.075825416385311	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: