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View Structure Prediction Details

Protein: ech-1
Organism: Caenorhabditis elegans
Length: 755 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ech-1.

Description E-value Query
Range
Subject
Range
gi|187029181, gi... - gi|39595637|emb|CAE67139.1| Hypothetical protein CBG12562 [Caenorhabditis briggsae], gi|187029181|em...
gi|157747409 - gi|157747409|ref|XP_001668799.1| Hypothetical protein CBG12562 [Caenorhabditis briggsae AF16]
718.0 [0..1] [755..1]

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Predicted Domain #1
Region A:
Residues: [1-755]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRVVHRSS SVFRTNLSFR LFSQSAFAVH STHRVEKQGD VAVMKIDLPN TTENVLNKAL  60
   61 FAEMNETLDR LQSDQSVKAI VVMSGKPNSF VAGADIQMFK AEKTAAGVSN LLREGQKQLL 120
  121 TIELSQKPIV AAIMGSCMGG GLEIALACHY RIAVNDKKTL LGLPEVTLGI MPGDGGTQRL 180
  181 PKLTTVQNVL DLTLTGKRIK ANKAMKIGIV DRVIQPLGDG ICTSTETTHK YLEEIAVQSA 240
  241 RELANGKLKI NRDKGFVHNA TQAVMTSKFV LDNVILKMAK NKLIKLTNGN YPAPLKILDV 300
  301 VRTAYLDPKN GYEAEAKAFG ELSQTFQSKA LFGLFEGSTN AKKNKYGKGL PVNEIAVVGA 360
  361 GFMGAGIANV TINKGIRTVL LDANQAGVER GQNHVATHLN RQLKRQKISK LEREKIYNHL 420
  421 VPTIDYSAMK NADVVIEAVF EDLPLKHKVI RQIENVVGPN TIIASNTSAL PIKDIAAASS 480
  481 RSDKVIGMHY FSPVEKMQLL EIITHDGTSK ETLATAAQLG LKQGKLVVVV KDCPGFFVVR 540
  541 CLSPMMSEIV RLLQEGVEPS ELDKLTTKFG FPVGAATLAD EAGLDVAEHV ARYLGTALGP 600
  601 RVHGGSVDLL SELVRAGHKG RKTSKGIFVY GDGAKGSKKV NQEAAKLFEK YKLTPIKSVS 660
  661 SPEDRQLRLV SRFVNEALLC LEEGVISSPS DGDIASVFGL GFPPFWGGPF RFVDLYGAGK 720
  721 LVAAMDRFAG VYESVQFEPC QLLRNHAKSG GQFYS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 175.0
Match: 1wdkA
Description: fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
3-hydroxybutyryl-CoA epimerase activity 6.21347266913168 bayes_pls_golite062009
long-chain-3-hydroxyacyl-CoA dehydrogenase activity 5.99914207874933 bayes_pls_golite062009
racemase and epimerase activity, acting on hydroxy acids and derivatives 5.93014177440654 bayes_pls_golite062009
long-chain-enoyl-CoA hydratase activity 5.38361434383109 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydratase activity 4.29069790566708 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 4.25084649365698 bayes_pls_golite062009
enoyl-CoA hydratase activity 3.92947460544831 bayes_pls_golite062009
CoA carboxylase activity 3.89913842968597 bayes_pls_golite062009
acetyl-CoA carboxylase activity 3.85567083340773 bayes_pls_golite062009
acetyl-CoA C-acyltransferase activity 3.6090947563188 bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds 3.4980371783229 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 3.02758902218302 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing C=C bonds 1.97586838275054 bayes_pls_golite062009
dodecenoyl-CoA delta-isomerase activity 1.80820904754223 bayes_pls_golite062009
catalytic activity 1.46154163027498 bayes_pls_golite062009
propionyl-CoA carboxylase activity 1.20853698666984 bayes_pls_golite062009
phosphogluconate dehydrogenase (decarboxylating) activity 1.10855899772836 bayes_pls_golite062009
ligase activity 0.98581896521131 bayes_pls_golite062009
binding 0.339935392509049 bayes_pls_golite062009
fatty acid synthase activity 0.0962368786590111 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle