| Protein: | acr-2 |
| Organism: | Caenorhabditis elegans |
| Length: | 575 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-2.
| Description | E-value | Query Range |
Subject Range |
|
|
425.0 | [0..1] | [575..1] |
|
Region A: Residues: [1-379] |
1 11 21 31 41 51
| | | | | |
1 MKKTVKILLI LITVFLKVHC NGGHDDEAAD FLSHTNIDDP NNSSDPNKNS DQGDTMGEDE 60
61 DRLVIDLFRE YNFLIRPVKN VSSPPVVVDF GVAMILLINV DEKNQILQTN VWLTMKWNDF 120
121 QLAWNPAEYG NISNLHVPSD RVWLPDIVLF NNADGNYEVS FKSNVFVDHH GDVTWVPPAM 180
181 FKSSCRIDVE WFPFDEQCCT LVFGSWTYNS EEVRLHWYNN IQAVQLHDYS YSGIWDVIDV 240
241 PGQLVHKPDL KENKMVFNVV IRRKTLFYTV ILIIPTVLMA FLSVMAFYLP VDSGEKVSLT 300
301 ISLLLALVVF LLLVSKILPP TSNIPLMGKY LLLAFVLNIT AVVGTVVIVN IYFRSALSHK 360
361 MPTWVRKVFL EFLPHLLVM
|
| Detection Method: |  |
| Confidence: | 76.522879 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [380-575] |
1 11 21 31 41 51
| | | | | |
1 KRPERIPIFN GYFVEEYCAS EIFDASLVMP SMTATMLPFL QVTTNLKAAS STSSGQSSEH 60
61 HENCSKWKKR LSIRMSKRRA PRARLDDDSE DIIDDTNGNH VDSLQEKISK EMKTTVEAIA 120
121 YIAEHMKREM SLKKMRDDWK YVAMVLDRLI LLIFFGVTLG GTLGIICSAP HVFDFVDQEA 180
181 IISKLNAKYL PSDMYS
|
| Detection Method: | |
| Confidence: | 38.30103 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetylcholine binding | 13.9752632471881 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 13.7533645836795 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 13.1511875247796 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 11.9525876011069 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| cation channel activity | 11.7442066737514 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| amine binding | 9.11982124959723 | bayes_pls_golite062009 |
| chloride channel regulator activity | 9.10587892909341 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 7.19173677417054 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| neurotransmitter binding | 4.25797760547212 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 4.15404686068319 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| adenylate cyclase binding | 3.30190657223613 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.25766805801029 | bayes_pls_golite062009 |
| 1.68370717591127 | bayes_pls_golite062009 | |
| channel regulator activity | 1.66978990310631 | bayes_pls_golite062009 |
| protein binding | 1.45740893920165 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.42422063123689 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| kinase binding | 0.365355763029699 | bayes_pls_golite062009 |
| protein kinase binding | 0.350601457777817 | bayes_pls_golite062009 |
