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View Structure Prediction Details

Protein: nas-10
Organism: Caenorhabditis elegans
Length: 560 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-10.

Description E-value Query
Range
Subject
Range
gi|39594918, gi|... - gi|39594918|emb|CAE70786.1| Hypothetical protein CBG17542 [Caenorhabditis briggsae], gi|187025699|em...
gi|157768568 - gi|157768568|ref|XP_001676105.1| Hypothetical protein CBG17542 [Caenorhabditis briggsae AF16]
545.0 [0..59] [560..18]

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Predicted Domain #1
Region A:
Residues: [1-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTITDLKTI NRKQKQAYLQ EKLICSRHCW LTHTTSKHIN IQWTTLIPHI RCRGFNNGPH  60
   61 PNSRPGSRPN SPLGDIFGNI NGMVKGITDQ IGKIAQGLDV NNDLGKMAHG PPPPQSEWVE 120
  121 HARRFCRRFP GHPKCRGQLP QFNDIGSMLN GILVDSGKWL PKVPFINIRD PLSGINSDLK 180
  181 NALNGIQVQF GQISQQFANN IRNICQQMNC KQQQQKNVQM KQAILKQTVD FEKKVFGNNV 240
  241 ADKMNLR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [248-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDRTLQLKQA LLEKAQLKGV VAPEDNGVFD KDLLLTETQA NFMLNELGKG GEGAIPMPGS  60
   61 AKAKRASIFF EQNLIQKWPS TSPIPYTFDS SLDNLDQNDV RGAISEIEQK TCIRFKYFAS 120
  121 PPKGNHINYQ KVNSPSFCGL SYIGRVEPAN PVYLSFQCGN GRGIAVHETM HALGVNHQHL 180
  181 RMDRDKHIKV DWSNINPQQY DAFVVADSKL YTTYGV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.09691
Match: 1ck7A
Description: Gelatinase A (MMP-2); Gelatinase A (MMP-2), C-terminal domain; Gelatinase A; Gelatinase A (MMP-2) type II modules
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 1.35763516872513 bayes_pls_golite062009
binding 0.827429924935597 bayes_pls_golite062009
protein binding 0.497523852978755 bayes_pls_golite062009
signal transducer activity 0.420287665033567 bayes_pls_golite062009
molecular transducer activity 0.420287665033567 bayes_pls_golite062009
metallopeptidase activity 0.201462065243776 bayes_pls_golite062009
peptidase activity 0.142007397056454 bayes_pls_golite062009
transmembrane receptor activity 0.136560284009247 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [464-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYAYDSIMHY NAYTGAVNIA KPTMIPLVNQ QANIGLLGQR AKMSNADVEI LNKMYCKSAG  60
   61 CDDKNVYCGA WALQDLCNNP NHNVWMRSNC RKSCNFC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.69897
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle