| Protein: | sex-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 534 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sex-1.
| Description | E-value | Query Range |
Subject Range |
|
|
347.0 | [0..1] | [527..23] |
|
Region A: Residues: [1-139] |
1 11 21 31 41 51
| | | | | |
1 MSFETKPNYL LLTNPDTPLS VCTSPYYSPS GKTASIPSSE ASKPEGTNGQ WSHLPTGATY 60
61 VTDEFSSEFQ IQNGSTAAQS GNANNYADPL SHRRYFNNVN GYNHHQFYDT ASQASVSSPA 120
121 TSVTSSLSPP DSLSNGHTT
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [140-227] |
1 11 21 31 41 51
| | | | | |
1 QRHHIGKAIS FCKVCGDKAS GYHYGVTSCE GCKGFFRRSI QRKIDYRCLK QQVCEIKRES 60
61 RNRCQYCRFK KCLDSGMSKD SVRQMKFR
|
| Detection Method: | |
| Confidence: | 20.522879 |
| Match: | 2hanB |
| Description: | No description for 2hanB was found. |
| Term | Confidence | Notes |
| transcription regulator activity | 4.00967542385368 | bayes_pls_golite062009 |
| DNA binding | 3.60745514727532 | bayes_pls_golite062009 |
| nucleic acid binding | 3.47256374293954 | bayes_pls_golite062009 |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription factor activity | 2.90769972671972 | bayes_pls_golite062009 |
| protein binding | 2.44501340584871 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.40923942043513 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.91348392022358 | bayes_pls_golite062009 |
| transcription repressor activity | 1.88834375049208 | bayes_pls_golite062009 |
| hormone receptor binding | 1.8288193687002 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 1.72196998170947 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.62841402245495 | bayes_pls_golite062009 |
| transcription activator activity | 1.62405765585032 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.49515149729803 | bayes_pls_golite062009 |
| androgen receptor binding | 1.48596869620742 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.46067968492906 | bayes_pls_golite062009 |
| transcription factor binding | 1.38523780690867 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 1.28090460550476 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.26452462867497 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.14370842685155 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 1.10242633521642 | bayes_pls_golite062009 |
| structural molecule activity | 1.03433454627943 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.979635034577337 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.58115018700114 | bayes_pls_golite062009 |
| receptor activity | 0.230063209127305 | bayes_pls_golite062009 |
| catalytic activity | 0.101795606736461 | bayes_pls_golite062009 |
|
Region A: Residues: [228-534] |
1 11 21 31 41 51
| | | | | |
1 NAMRDDKSPD SVFVPEISTL ERQEEVDAVY EAVLRAHTTF SFYTDIKIRS IVARPFNVRI 60
61 NEDSKMNRLN AWQIYAHEID VDIKEVVNFV KEIPKFNFIN GNDKAVLLRK NAFPLYLLRI 120
121 VRGMSNRGLM LRDGRLIDFK SLQLLYGSLA DEMLAFANHI ITIGCTDGDI ALFIVLILCQ 180
181 PLTTEQQFST NFKSQLQLLE MFDFYKKVLF QKMTCRIDGC DTYKQLMKCI HELNRLNELH 240
241 KQQLNILREN LSFLNLPPLV VEMFQLSTLP LPVNHNNQEN QYTPAPEHQS PQPQQPTPNQ 300
301 QQTPVHC
|
| Detection Method: | |
| Confidence: | 50.0 |
| Match: | 1xdkB |
| Description: | Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| vitamin D3 receptor activity | 5.5563493713822 | bayes_pls_golite062009 |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 4.81441024181511 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 4.66615836207965 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 3.91470119037087 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| hormone receptor binding | 3.79647267365529 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator activity | 3.20381581407476 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.01488410150634 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| vitamin D binding | 2.05947211013242 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| prostacyclin receptor activity | 1.74944518684208 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.56146647486761 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.48246587604476 | bayes_pls_golite062009 |
| estrogen receptor activity | 1.47290778095383 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.23834725221597 | bayes_pls_golite062009 |
| promoter binding | 1.16363620574097 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| juvenile hormone binding | 0.814202236506491 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.754240851368212 | bayes_pls_golite062009 |
| steroid binding | 0.687964316511791 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| retinoid binding | 0.234953048620166 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| isoprenoid binding | 0.190887599354128 | bayes_pls_golite062009 |
| lipid binding | 0.164046651023989 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
| estrogen response element binding | 4.73336420190096E-4 | bayes_pls_golite062009 |
