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View Structure Prediction Details

Protein: rpn-9
Organism: Caenorhabditis elegans
Length: 387 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpn-9.

Description E-value Query
Range
Subject
Range
gi|157502193, gi... - gi|3618343|dbj|BAA33214.1| 26S proteasome subunit p40.5 [Homo sapiens], gi|157502193|ref|NP_002808.3...
309.0 [0..3] [385..4]

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Predicted Domain #1
Region A:
Residues: [1-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAQDYLNGK LAAANGPLAD DWKNLKELWE KKLWHQLTVL TRSLVKKPQF VASTDMHEFY  60
   61 RLFVAEWELR VNPLQLVEIC ISIAQNIATK DKQKSMEFLS KIGNVINKDK IAVARLHTGE 120
  121 IEARLENKDK NGQIIDLKSI RTQIDSTQHE VDSLVGVTEV HAPFYRVSSL YLREVGDFAG 180
  181 YYREALRYLG VEDANNLTTE Q

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [202-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQVHAVLLGF AALLGENVHN FGELLAHPIL KSLEGTRERW IVDVLLAFNS GDLTRFFSLE  60
   61 GDWGGW

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [268-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDLKKQKDFL TAKIRLMAVM ELAVSRPTKA RSVSFKEIAT KCQIPFDEVE FLVMKALSKD  60
   61 LIRGDINQVE QVVYVTWVQP RVLDNPQIMQ MATRISAWRN DVNSMEGIVS KEAREILTQN 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.045757
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.77201910025409 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
DNA binding 3.44642410378325 bayes_pls_golite062009
nucleic acid binding 3.38144578566524 bayes_pls_golite062009
transcription factor activity 2.83460075788873 bayes_pls_golite062009
hydrolase activity 2.30467124306022 bayes_pls_golite062009
sequence-specific DNA binding 2.08341148210578 bayes_pls_golite062009
transcription activator activity 1.98504395280033 bayes_pls_golite062009
transcription repressor activity 1.16843113623321 bayes_pls_golite062009
protein binding 0.753698599635855 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.42135864069093 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.136726704233672 bayes_pls_golite062009
small conjugating protein ligase activity 0.118016217031359 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle