| Protein: | sir-2.2 |
| Organism: | Caenorhabditis elegans |
| Length: | 287 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sir-2.2.
| Description | E-value | Query Range |
Subject Range |
|
|
314.0 | [0..1] | [287..1] |
|
|
314.0 | [0..1] | [287..1] |
|
|
311.0 | [0..5] | [285..33] |
|
|
311.0 | [0..5] | [285..30] |
|
|
309.0 | [0..5] | [285..32] |
|
|
309.0 | [0..5] | [285..13] |
|
|
309.0 | [0..5] | [285..114] |
|
|
308.0 | [0..5] | [285..32] |
|
Region A: Residues: [1-287] |
1 11 21 31 41 51
| | | | | |
1 MAQKFVPEAA ELCENSLKKF ISLIGTVDKL LVISGAGIST ESGIPDYRSK DVGLYARIAH 60
61 KPIYFQDYMR SNRCRQRYWS RNFLAWPRFG QAAPNINHYA LSKWEASDRF QWLITQNVDG 120
121 LHLKAGSKMV TELHGSALQV KCTTCDYIES RQTYQDRLDY ANPGFKEEHV APGELAPDGD 180
181 IILPLGTEKG FQIPECPSCG GLMKTDVTFF GENVNMDKVN FCYEKVNECD GILSLGTSLA 240
241 VLSGFRFIHH ANMKKKPIFI VNIGPTRADH MATMKLDYKI SDVLKEM
|
| Detection Method: |  |
| Confidence: | 74.69897 |
| Match: | 1ma3A |
| Description: | AF0112, Sir2 homolog (Sir2-AF2) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| NAD-dependent histone deacetylase activity | 4.66387831647923 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 4.66387831647923 | bayes_pls_golite062009 |
| NAD+ ADP-ribosyltransferase activity | 4.62921662347995 | bayes_pls_golite062009 |
| histone deacetylase activity | 4.52265070993834 | bayes_pls_golite062009 |
| protein deacetylase activity | 4.51418609991523 | bayes_pls_golite062009 |
| deacetylase activity | 3.60611826633675 | bayes_pls_golite062009 |
| transcription regulator activity | 2.31731368009317 | bayes_pls_golite062009 |
| DNA binding | 1.84059392605809 | bayes_pls_golite062009 |
| nucleic acid binding | 1.83132687449755 | bayes_pls_golite062009 |
| transcription repressor activity | 1.74876325396581 | bayes_pls_golite062009 |
| binding | 1.63619372613603 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 1.38412624618353 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.16656035070431 | bayes_pls_golite062009 |
| transporter activity | 1.02987325768951 | bayes_pls_golite062009 |
| NAD(P)+-protein-arginine ADP-ribosyltransferase activity | 0.963519974868694 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.879539673228343 | bayes_pls_golite062009 |
| transcription factor activity | 0.758967814548108 | bayes_pls_golite062009 |
| catalytic activity | 0.739210399081789 | bayes_pls_golite062009 |
| transcription factor binding | 0.64778523540991 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.62029498163975 | bayes_pls_golite062009 |
| histone binding | 0.60825982588532 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.56000396203236 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.52020182886741 | bayes_pls_golite062009 |
| protein binding | 0.475479132768057 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.47231237137431 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.128843577740998 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 0.114062221123972 | bayes_pls_golite062009 |
| hydrolase activity | 0.0875567934348688 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.05634462944063 | bayes_pls_golite062009 |
