| Protein: | sir-2.3 |
| Organism: | Caenorhabditis elegans |
| Length: | 287 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sir-2.3.
| Description | E-value | Query Range |
Subject Range |
|
|
311.0 | [0..1] | [287..1] |
|
|
306.0 | [0..1] | [287..1] |
|
|
302.0 | [0..5] | [285..33] |
|
|
301.0 | [0..5] | [285..30] |
|
|
300.0 | [0..5] | [285..32] |
|
|
300.0 | [0..5] | [285..114] |
|
|
299.0 | [0..5] | [285..13] |
|
|
299.0 | [0..5] | [285..32] |
|
Region A: Residues: [1-287] |
1 11 21 31 41 51
| | | | | |
1 MARKYVPHTT ELCENSLKKF KSLVGTVDKL LIITGAGIST ESGIPDYRSK DVGLYTKTAL 60
61 EPIYFQDFMK SKKCRQRYWS RSYLNWPRFA QALPNFNHYA LSKWEAANKF HWLITQNVDG 120
121 LHLKAGSKMI TELHGNALQV KCTSCEYIET RQTYQDRLNY ANPGFKEQFV SPGQQELDAD 180
181 TALPLGSEQG FKIPECLNCG GLMKTDVTLF GENLNTDKIK VCGKKVNECN GVLTLGTSLE 240
241 VLSGYQIVNH AHMQNKPIFI VNIGPTRADQ MATMKLDYRI SDVLKEM
|
| Detection Method: |  |
| Confidence: | 74.69897 |
| Match: | 1ma3A |
| Description: | AF0112, Sir2 homolog (Sir2-AF2) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| NAD-dependent histone deacetylase activity | 4.66387831647923 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 4.66387831647923 | bayes_pls_golite062009 |
| NAD+ ADP-ribosyltransferase activity | 4.62921662347995 | bayes_pls_golite062009 |
| histone deacetylase activity | 4.52265070993834 | bayes_pls_golite062009 |
| protein deacetylase activity | 4.51418609991523 | bayes_pls_golite062009 |
| deacetylase activity | 3.60611826633675 | bayes_pls_golite062009 |
| transcription regulator activity | 2.31731368009317 | bayes_pls_golite062009 |
| DNA binding | 1.84059392605809 | bayes_pls_golite062009 |
| nucleic acid binding | 1.83132687449755 | bayes_pls_golite062009 |
| transcription repressor activity | 1.74876325396581 | bayes_pls_golite062009 |
| binding | 1.63619372613603 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 1.38412624618353 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.16656035070431 | bayes_pls_golite062009 |
| transporter activity | 1.02987325768951 | bayes_pls_golite062009 |
| NAD(P)+-protein-arginine ADP-ribosyltransferase activity | 0.963519974868694 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.879539673228343 | bayes_pls_golite062009 |
| transcription factor activity | 0.758967814548108 | bayes_pls_golite062009 |
| catalytic activity | 0.739210399081789 | bayes_pls_golite062009 |
| transcription factor binding | 0.64778523540991 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.62029498163975 | bayes_pls_golite062009 |
| histone binding | 0.60825982588532 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.56000396203236 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.52020182886741 | bayes_pls_golite062009 |
| protein binding | 0.475479132768057 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.47231237137431 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.128843577740998 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 0.114062221123972 | bayes_pls_golite062009 |
| hydrolase activity | 0.0875567934348688 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.05634462944063 | bayes_pls_golite062009 |
