YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: trf1
Organism: Schizosaccharomyces pombe
Length: 485 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for trf1.

Description E-value Query
Range
Subject
Range
gi|45185782, gi|... - gi|45185782|ref|NP_983498.1| ACR096Wp [Ashbya gossypii ATCC 10895], gi|44981537|gb|AAS51322.1| ACR09...
gi|44981537 - gi|44981537|gb|AAS51322.1| ACR096Wp [Ashbya gossypii ATCC 10895]
458.0 [0..89] [485..28]
gi|4604 - gi|4604|emb|CAA49191.1| TBF1 protein [Saccharomyces cerevisiae]
434.0 [0..93] [484..40]
TBF1_CANAL - Transcription factor TBF1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TBF1 PE=1 SV=1
orf19.801 - orf19.801 CGDID:CAL0002606 Assembly 19, Contig19-10076 (26861, 24201) CDS, reverse complemented, tra...
421.0 [0..89] [480..306]
gi|38103443, gi|... - gi|39943776|ref|XP_361425.1| hypothetical protein MGG_03899 [Magnaporthe grisea 70-15], gb|EAA50140....
401.0 [0..22] [430..281]
gi|49654064, gi|... - gi|50419739|ref|XP_458398.1| hypothetical protein DEHA0C17578g [Debaryomyces hansenii CBS767], gi|49...
357.0 [0..85] [485..335]
gi|85082158 - gi|85082158|ref|XP_956863.1| hypothetical protein NCU03416 [Neurospora crassa OR74A]
gi|32404122, gi|... - gi|32404122|ref|XP_322674.1| hypothetical protein [Neurospora crassa], gi|28917942|gb|EAA27627.1| pr...
354.0 [0..14] [316..171]
gi|42545050, gi|... - gi|46109150|ref|XP_381633.1| hypothetical protein FG01457.1 [Gibberella zeae PH-1], gi|42545050|gb|E...
342.0 [0..7] [319..50]
gi|49646905, gi|... - gi|50547139|ref|XP_501039.1| YALI0B18018p [Yarrowia lipolytica], gi|49646905|emb|CAG83292.1| unnamed...
gi|49646905 - gi|49646905|emb|CAG83292.1| YALI0B18018p [Yarrowia lipolytica]
330.0 [0..92] [484..141]

Back

Predicted Domain #1
Region A:
Residues: [1-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRSLDPSD DFKGQKRLAI DPESTALEQD RQMLQQLSEQ NSELEPQNVA PNAEIPLGFD  60
   61 LSGIQFNMTP DFYLRMNQGM DYAFNQPNPI ATPQQLLRTS LIPTLGNLSN IILSILGKPV 120
  121 QEASAIVTNP ASEMGMAFTK VMNMFRMVKD IYTEESFIYS SAIGMRTPSQ RSTTRRANLA 180
  181 IFLAAVYGAL QIGFFHLNEN FLEVFAPDES NILTNQGTLY MELKTQAYIS AMAQAERPKG 240
  241 DILNDLFPSD MAHRFLIRRN AKLDDKLTYV EKQIIEKCTA RKERLANFSP QEALNEVYPW 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [301-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKFLSEIACY IHNNYSSISA IPIPANSFKR RSKKNGLRFK AGEAESSPSE SGSDLTDSLA  60
   61 FGIPSSTFDG SSETQNVSSV V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [382-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYDQVRHMTN NNLNNKRTRR VANRRSWTKE EEEALLDGLD LVKGPRWSQI LELYGPGGKK  60
   61 SEVLKYRNQV QLKDKARNMK LFFLKSGQVV PAALQCVTGD LRRD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 1iv6A
Description: DNA-binding domain of human telomeric protein, hTRF1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
telomeric DNA binding 2.54876676195978 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.68956710349366 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
DNA-dependent ATPase activity 0.666799964992178 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.529774583092406 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009
cytoskeletal protein binding 0.236060274498333 bayes_pls_golite062009
DNA helicase activity 0.187022204923867 bayes_pls_golite062009
structure-specific DNA binding 0.105174598157041 bayes_pls_golite062009
histone binding 0.0391625783266718 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle