YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC105.03c
Organism:	Schizosaccharomyces pombe
Length:	708 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC105.03c.

Description	E-value	Query Range	Subject Range
YL8B_SCHPO - Uncharacterized transcriptional regulatory protein C25B8.11 OS=Schizosaccharomyces pombe (strain 972... SPAC25B8.11 - transcription factor	280.0	[0..110]	[696..8]
gi\|116196226, gi... - gi\|88180624\|gb\|EAQ88092.1\| hypothetical protein CHGG_04711 [Chaetomium globosum CBS 148.51], gi\|1161...	254.0	[0..76]	[699..4]
gi\|67536776, gi\|... - gi\|67536776\|ref\|XP_662162.1\| hypothetical protein AN4558.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	252.0	[0..69]	[703..17]
gi\|85081614 - gi\|85081614\|ref\|XP_956755.1\| hypothetical protein NCU01478 [Neurospora crassa OR74A] gi\|28917831, gi\|... - gi\|32414875\|ref\|XP_327917.1\| hypothetical protein [Neurospora crassa], gi\|28917831\|gb\|EAA27519.1\| hy...	251.0	[0..119]	[705..61]
gi\|169775145 - gi\|169775145\|ref\|XP_001822040.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83769903 - gi\|83769903\|dbj\|BAE60038.1\| unnamed protein product [Aspergillus oryzae]	248.0	[0..77]	[687..21]
gi\|245224 - gi\|245224\|gb\|AAB21394.1\| NIT4=protein product involved in nitrate assimilation [Neurospora intermedi... NIT4_NEUCR - Nitrogen assimilation transcription factor nit-4 - Neurospora crassa	248.0	[0..84]	[699..10]
gi\|119194841, gi... - gi\|90306810\|gb\|EAS36441.1\| hypothetical protein CIMG_01795 [Coccidioides immitis RS], gi\|119194841\|r...	247.0	[0..75]	[705..17]

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Predicted Domain #1

Region A:
Residues: [1-85]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQSSSPSQP ESQAQPNLCI PCSLGTCLIH FHEFSSSSFM DPVSLFCSSP YPNLPPHSRS  60
   61 SSLESKKPSV ASQDVKSDGT LPIGT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [86-262]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNNPLIPSHS QESSHWTIRH ESMPSALAGS SAQSMQQFPS ITQNEENFRF KKSFTQPQPI  60
   61 VKETTFPKSE PGQEHAKLSD LSYEEFLKKY SSTKVERVSE AAPPPSSLNS STVLDENDSL 120
  121 ISQGSSVDDQ TDFLGFDDSL SYAYILNPTS DSDVDLIRQY FIPKEGTYTF SNMHIRY

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.13
Match:	1pyiA
Description:	PPR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.34861813464065	bayes_pls_golite062009
DNA binding	4.03985756894684	bayes_pls_golite062009
nucleic acid binding	3.97978190843512	bayes_pls_golite062009
transcription factor activity	2.87348461329489	bayes_pls_golite062009
binding	2.82809978070212	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.70904317608141	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	2.08956709478484	bayes_pls_golite062009
sequence-specific DNA binding	1.67344049333457	bayes_pls_golite062009
transcription activator activity	0.822069987038721	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [263-389]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSANPKTPVM YMVDPAYEPH KQIARYEKLQ QIFQVVEATV SPEVGERLIG LYFRYIHRVY  60
   61 PVIHGERFLL AFKKAKHKLS PILLTAMYAS SIIYWDADKE LRNYPRLDAK KLWDLTEDFL 120
  121 DLSFSLS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [390-604]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLSTLQAAII FLTGRPWINV AGNWSILTRA IALAQILGFH LDCSEWQIPK EEKILRNRVW  60
   61 WALFVNEKWL SMYIGINASI RQDDYLVPPL TDNQLLAGEQ RIADSFNVFV KMAELSILLQ 120
  121 NVLQHLFNAR AVMTMSKNRR TVAQKISKYL ISLEEFSCSC NLRENQPGSL SLFLQIDALE 180
  181 LLLRKTALKL KLTDAVYQQE MLNVVQRCVS HFLAI

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [605-708]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NESHFTDFFW PYSQFYFCIL SSAIIKMYLD FEFNENFNAT TFGLLSSFTK HCVWLKFRNF  60
   61 DLVFMAYKRL NALLIELSSG RPLIGKLLQE TFEHRKRNLD ETLT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: