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View Structure Prediction Details

Protein: SPBC725.08
Organism: Schizosaccharomyces pombe
Length: 609 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC725.08.

Description E-value Query
Range
Subject
Range
gi|16198279 - gi|16198279|gb|AAL13972.1| LP08544p [Drosophila melanogaster]
503.0 [0..39] [600..143]
SRRT_CAEBR - Serrate RNA effector molecule homolog OS=Caenorhabditis briggsae GN=CBG12064 PE=3 SV=1
491.0 [0..11] [602..13]
gi|42544805, gi|... - gi|46108448|ref|XP_381282.1| hypothetical protein FG01106.1 [Gibberella zeae PH-1], gi|42544805|gb|E...
485.0 [0..19] [587..53]
CE20643 - status:Confirmed UniProt:Q966L5 protein_id:AAK85459.1
481.0 [0..21] [602..29]
gi|85113061 - gi|85113061|ref|XP_964456.1| hypothetical protein [Neurospora crassa OR74A]
gi|28926239, gi|... - gi|32419020|ref|XP_329988.1| hypothetical protein [Neurospora crassa], gi|28926239|gb|EAA35220.1| hy...
473.0 [0..17] [577..82]
gi|38110174, gi|... - gi|39951887|ref|XP_363660.1| hypothetical protein MG01586.4 [Magnaporthe grisea 70-15], gb|EAA55935....
472.0 [0..18] [577..58]
gi|67901114, gi|... - gi|67901114|ref|XP_680813.1| hypothetical protein AN7544.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
451.0 [0..99] [575..3]
gi|33875203 - gi|33875203|gb|AAH00082.2| SRRT protein [Homo sapiens]
444.0 [0..220] [602..15]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVHQESEV EYSRWKRERS PERSQRRSQS PPGEQSAYHR ERSPLRKRGN YYDDRTRASG  60
   61 PYPTFTKPLI DPYTQTNAVS YERFIRWYSK ENHISATTED LYNSLHGTYN NYKQDLYART 120
  121 ARSFVESHCD EAWFEDSY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [139-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WVDESQGRVL EVSENEKSYR RALYDKFMDR LDAGYYDDFQ LPTAEDVIEK PSIPDNDTDD  60
   61 SILPSNDPQL SKWNQDSRND AMENTLLVSH VLPNISVAQI HNALDGISFV QHFSLSTINL 120
  121 IKNDERSLWV HFKAGTNMDG AKEAVDGIQL DSNFTIESEN PKIPTHTHPI PIFEIASSEQ 180
  181 TCKNLLEKLI RFIDRA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.06
Match: 1hl6A
Description: CG8781 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.65259034341669 bayes_pls_golite062009
binding 3.48033873254013 bayes_pls_golite062009
RNA binding 2.51560202858525 bayes_pls_golite062009
transcription regulator activity 2.2045206027152 bayes_pls_golite062009
DNA binding 1.99030664201171 bayes_pls_golite062009
mRNA binding 1.52376515340629 bayes_pls_golite062009
transcription repressor activity 1.26023364760328 bayes_pls_golite062009
transcription factor activity 1.09958329302628 bayes_pls_golite062009
protein binding 1.05805521997665 bayes_pls_golite062009
sequence-specific DNA binding 0.327072171076297 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [335-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STKYSLPNDA AQRIEDRLKT HASMKDDDDK PTNFHDIRLS DLYAEYLRQV ATFDFWTSKE  60
   61 YESLIALLQD S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [406-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAGYSRKKFN PSKEVGQEEN IWLSDLENNF ACLLEPENVD IKAKGALPVE DFINNELDSV  60
   61 IMKEDEQKYR CHVGTCAKLF LGPEFVRKHI NKKHKDWLDH IKKVAICLYG YVLDPCRAMD 120
  121 PKVVSTSYVS LQILNKPYVG FRNINANYTF PTTSYSRRND EEITSGASSQ KSYSRQEPMI 180
  181 HRREFYRTYQ DLDAPNQEVP ELDY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle