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View Structure Prediction Details

Protein: SPBC725.08
Organism: Schizosaccharomyces pombe
Length: 609 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC725.08.

Description E-value Query
Range
Subject
Range
gi|16198279 - gi|16198279|gb|AAL13972.1| LP08544p [Drosophila melanogaster]
503.0 [0..39] [600..143]
SRRT_CAEBR - Serrate RNA effector molecule homolog OS=Caenorhabditis briggsae GN=CBG12064 PE=3 SV=1
491.0 [0..11] [602..13]
gi|42544805, gi|... - gi|46108448|ref|XP_381282.1| hypothetical protein FG01106.1 [Gibberella zeae PH-1], gi|42544805|gb|E...
485.0 [0..19] [587..53]
CE20643 - status:Confirmed UniProt:Q966L5 protein_id:AAK85459.1
481.0 [0..21] [602..29]
gi|85113061 - gi|85113061|ref|XP_964456.1| hypothetical protein [Neurospora crassa OR74A]
gi|28926239, gi|... - gi|32419020|ref|XP_329988.1| hypothetical protein [Neurospora crassa], gi|28926239|gb|EAA35220.1| hy...
473.0 [0..17] [577..82]
gi|38110174, gi|... - gi|39951887|ref|XP_363660.1| hypothetical protein MG01586.4 [Magnaporthe grisea 70-15], gb|EAA55935....
472.0 [0..18] [577..58]
gi|67901114, gi|... - gi|67901114|ref|XP_680813.1| hypothetical protein AN7544.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
451.0 [0..99] [575..3]
gi|33875203 - gi|33875203|gb|AAH00082.2| SRRT protein [Homo sapiens]
444.0 [0..220] [602..15]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVHQESEV EYSRWKRERS PERSQRRSQS PPGEQSAYHR ERSPLRKRGN YYDDRTRASG  60
   61 PYPTFTKPLI DPYTQTNAVS YERFIRWYSK ENHISATTED LYNSLHGTYN NYKQDLYART 120
  121 ARSFVESHCD EAWFEDSY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [139-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WVDESQGRVL EVSENEKSYR RALYDKFMDR LDAGYYDDFQ LPTAEDVIEK PSIPDNDTDD  60
   61 SILPSNDPQL SKWNQDSRND AMENTLLVSH VLPNISVAQI HNALDGISFV QHFSLSTINL 120
  121 IKNDERSLWV HFKAGTNMDG AKEAVDGIQL DSNFTIESEN PKIPTHTHPI PIFEIASSEQ 180
  181 TCKNLLEKLI RFIDRA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.06
Match: 1hl6A
Description: CG8781 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.65259034341669 bayes_pls_golite062009
binding 3.48033873254013 bayes_pls_golite062009
RNA binding 2.51560202858525 bayes_pls_golite062009
transcription regulator activity 2.2045206027152 bayes_pls_golite062009
DNA binding 1.99030664201171 bayes_pls_golite062009
mRNA binding 1.52376515340629 bayes_pls_golite062009
transcription repressor activity 1.26023364760328 bayes_pls_golite062009
transcription factor activity 1.09958329302628 bayes_pls_golite062009
protein binding 1.05805521997665 bayes_pls_golite062009
sequence-specific DNA binding 0.327072171076297 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [335-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STKYSLPNDA AQRIEDRLKT HASMKDDDDK PTNFHDIRLS DLYAEYLRQV ATFDFWTSKE  60
   61 YESLIALLQD S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [406-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAGYSRKKFN PSKEVGQEEN IWLSDLENNF ACLLEPENVD IKAKGALPVE DFINNELDSV  60
   61 IMKEDEQKYR CHVGTCAKLF LGPEFVRKHI NKKHKDWLDH IKKVAICLYG YVLDPCRAMD 120
  121 PKVVSTSYVS LQILNKPYVG FRNINANYTF PTTSYSRRND EEITSGASSQ KSYSRQEPMI 180
  181 HRREFYRTYQ DLDAPNQEVP ELDY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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