YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC18B5.05c
Organism:	Schizosaccharomyces pombe
Length:	327 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC18B5.05c.

Description	E-value	Query Range	Subject Range
gi\|28211403, gi\|... - gi\|28211403\|ref\|NP_782347.1\| hydroxymethylpyrimidine kinase [Clostridium tetani E88], gi\|28203844\|gb...	236.0	[0..7]	[293..1]
gi\|149948927, gi... - gi\|77686688\|ref\|ZP_00802021.1\| Phosphomethylpyrimidine kinase [Alkaliphilus metalliredigenes QYMF], ...	231.0	[0..13]	[300..1]
gi\|106895590, gi... - gi\|158321715\|ref\|YP_001514222.1\| phosphomethylpyrimidine kinase [Alkaliphilus oremlandii OhILAs], gi...	229.0	[0..13]	[293..1]
gi\|22135970 - gi\|22135970\|gb\|AAM91567.1\| phosphomethylpyrimidine kinase [Arabidopsis thaliana]	226.0	[0..2]	[300..18]
gi\|110802744, gi... - gi\|110802744\|ref\|YP_698658.1\| phosphomethylpyrimidine kinase [Clostridium perfringens SM101], gi\|110...	225.0	[0..15]	[293..6]
gi\|18313413, gi\|... - gi\|18313413\|ref\|NP_560080.1\| phosphomethylpyrimidine kinase [Pyrobaculum aerophilum str. IM2], gi\|18...	224.0	[0..15]	[327..4]
gi\|255517037 - gi\|255517037\|ref\|ZP_05384713.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-9... gi\|255650139 - gi\|255650139\|ref\|ZP_05397041.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-3... gi\|115250640, gi... - gi\|126699203\|ref\|YP_001088100.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile 630]... gi\|254975231 - gi\|254975231\|ref\|ZP_05271703.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-6... gi\|255092621 - gi\|255092621\|ref\|ZP_05322099.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile CIP 1... gi\|255100727 - gi\|255100727\|ref\|ZP_05329704.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-6... gi\|255314358 - gi\|255314358\|ref\|ZP_05355941.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-7...	223.0	[0..17]	[294..9]
SPBP8B7.18c - phosphomethylpyrimidine kinase THI22_SCHPO - Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2 OS=Schizosaccharomyces pombe (stra...	222.0	[0..11]	[293..33]
gi\|98661660 - gi\|98661660\|dbj\|GAA01368.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	221.0	[0..12]	[295..64]

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Predicted Domain #1

Region A:
Residues: [1-327]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEANQSHNAK TNHPTCLTIA GSDCSGAAGI QADLKVMTAH QVYGMSVLTA LTCQNSHGIT  60
   61 GIYPLHPSLI QRQIDACLSD IQCRVVKIGM LPDPKSIPVI SQALTKYKIT DVVMDSVIIS 120
  121 SMGNVMCETP TIPATIQHLF PHLLVYASNV MEAFILVEKT LKKSPPPLKS FPDIQNLMSI 180
  181 IHRLGPKFVV LRGHHVAFDK NMMITEKPDS KSWTADLIYD GKEFYIFEKP YNTTKSIHGE 240
  241 SCSLTAAIAS NLACNIPPLQ AIHEALYSIE WAIQRVHKKS SDPYKSAQLF TALGHSSKFS 300
  301 GSLISLKSEN YIPQADLTSV LLSHIPS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.0
Match:	1jxhA
Description:	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphomethylpyrimidine kinase activity	3.972577109569	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	2.29466565429735	bayes_pls_golite062009
kinase activity	2.28531824242987	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.27980720248925	bayes_pls_golite062009
transferase activity	2.15883296431019	bayes_pls_golite062009
catalytic activity	1.74474587246986	bayes_pls_golite062009
hydroxyethylthiazole kinase activity	1.28568044601242	bayes_pls_golite062009
thiamin-phosphate diphosphorylase activity	1.27602595951972	bayes_pls_golite062009
carbohydrate kinase activity	1.12876288824319	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.673555832721854	bayes_pls_golite062009
nucleic acid binding	0.35385659578167	bayes_pls_golite062009
binding	0.2717506679077	bayes_pls_golite062009
transcription regulator activity	0.219913271321955	bayes_pls_golite062009
pyridoxal kinase activity	0.217863391052366	bayes_pls_golite062009
DNA binding	0.101423482181266	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: