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Protein Overview: THI22_SCHPO

General Information:
Name(s) found: THI22_SCHPO [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBP8B7.18c PE=3 SV=1 [Swiss-Prot]
    • Organism: Schizosaccharomyces pombe 972h-
    Length: 551 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYNPLYESL SNQFDPSRIE TVLDPMGYTI KRRALPVSLT IAGSDCSGGA GIQADLKTMT  60
   61 SLGVYGMSAI TCLVAENAGG VDSVEEMSPA FVESQIDCCI RDIPCHVVKT GMLGSPEIVK 120
  121 AVARSAKKFN FSKLVVDPVM VATSGDSLVT KDIVSVLNEE LLPLTYLVTP NIPEAIVLAK 180
  181 NQGLDISNIN SVSDMERCAA VIHKLGPKHV LLKGGHMPVN NLGLKSSDDE DLRVVDILYD 240
  241 GNRFYHFSSS YLKKGEVHGT GCTLSSAIAS FLAWEHSLTE AVQFGIDYVH GAITHSPPIN 300
  301 NCSTNILNHM TRLRIVPFAP GHFIEYILSH PQVVPAWKEY INHKFTNMLA KGTLPLPAFQ 360
  361 DYLKQDYLYL VNFARAYSLK GYKENTFPNI LEAAQSVIHV IEEKELHVSM CSSYGVSLQD 420
  421 LKSCEESPAC TAYSRYILDT GAAQDVAALD FVQAPCLIGY YVIAARLMKE PFRNPQGPYQ 480
  481 KWVDNYFCED YLSAVRRGCR QIEEIVLKLS PERIQELIEI FIRATKFETL FWETPYYEYV 540
  541 TKQNLEDKEF S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..317] PSI-BLAST 54.221849 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD)
    2 View Details [318..551] PSI-BLAST 56.154902 Structure of TenA from Bacillus subtilis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphomethylpyrimidine kinase activity
    		•  3.972577109569 bayes_pls_golite062009
  • kinase activity
    		•  2.74755351135221 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.43969902311075 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  2.34445983129813 bayes_pls_golite062009
  • thiaminase activity
    		•  2.33383885490808 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.31951903725366 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  2.29466565429735 bayes_pls_golite062009
  • transferase activity
    		•  2.15883296431019 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.14277879659132 bayes_pls_golite062009
  • DNA binding
    		•  1.96007866678724 bayes_pls_golite062009
  • catalytic activity
    		•  1.74474587246986 bayes_pls_golite062009
  • binding
    		•  1.4216897826135 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.37866801006693 bayes_pls_golite062009
  • hydroxyethylthiazole kinase activity
    		•  1.28568044601242 bayes_pls_golite062009
  • thiamin-phosphate diphosphorylase activity
    		•  1.27602595951972 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22047633822494 bayes_pls_golite062009
  • phosphofructokinase activity
    		•  0.37205329607884 bayes_pls_golite062009
  • pyridoxal kinase activity
    		•  0.217863391052366 bayes_pls_golite062009
  • protein binding
    		•  0.117280046908929 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  2.47421036599568 bayes_pls_golite062009
  • binding
    		•  1.80342520508546 bayes_pls_golite062009
  • transcription activator activity
    		•  0.765671114434415 bayes_pls_golite062009
  • catalytic activity
    		•  0.476060647762462 bayes_pls_golite062009
  • protein binding
    		•  0.438212622992804 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle