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View Structure Prediction Details

Protein: SPBC83.05
Organism: Schizosaccharomyces pombe
Length: 773 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC83.05.

Description E-value Query
Range
Subject
Range
gi|46107906, gi|... - gi|46107906|ref|XP_381012.1| hypothetical protein FG00836.1 [Gibberella zeae PH-1], gi|42547586|gb|E...
772.0 [0..13] [771..39]
gi|49095626, gi|... - gi|67537934|ref|XP_662741.1| hypothetical protein AN5137.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
767.0 [0..23] [770..30]
YME2_NEUCR - Mitochondrial escape protein 2 OS=Neurospora crassa GN=yme-2 PE=3 SV=1
YME2_NEUCR - Mitochondrial escape protein 2 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / D...
755.0 [0..37] [771..92]
YME2_ASHGO - Mitochondrial escape protein 2 OS=Ashbya gossypii GN=YME2 PE=3 SV=1
YME2_ASHGO - Mitochondrial escape protein 2 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL...
737.0 [0..30] [769..40]
YME2_MAGO7 - Mitochondrial escape protein 2 OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=Y...
YME2_MAGGR - Mitochondrial escape protein 2 OS=Magnaporthe grisea GN=YME2 PE=3 SV=1
722.0 [0..11] [771..8]
YME2_YEAST - Mitochondrial escape protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YME2 PE=1...
YME2 - Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid stru...
703.0 [0..24] [767..51]
YME2_ASPOR - Mitochondrial escape protein 2 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) GN=yme2 PE=3 SV=1
YME2_ASPOR - Mitochondrial escape protein 2 OS=Aspergillus oryzae GN=yme2 PE=3 SV=1
692.0 [0..37] [771..83]
YME2_CHAGB - Mitochondrial escape protein 2 OS=Chaetomium globosum GN=YME2 PE=3 SV=1
YME2_CHAGB - Mitochondrial escape protein 2 OS=Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NB...
692.0 [0..28] [771..50]
gi|115385855, gi... - gi|115385855|ref|XP_001209474.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
682.0 [0..28] [772..32]
gi|70991266, gi|... - gi|70991266|ref|XP_750482.1| RNA12 protein [Aspergillus fumigatus Af293], gi|66848114|gb|EAL88444.1|...
gi|159130955 - gi|159130955|gb|EDP56068.1| RNA12 protein, putative [Aspergillus fumigatus A1163]
676.0 [0..28] [769..80]

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Predicted Domain #1
Region A:
Residues: [1-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLFLSRFTG LRNTSFLGHA RPFMFPRRYA HSLVAHNIGH IKLDPNEGLF FVDNLVNTPT  60
   61 YFYIQRYTAL LFQNNLKKQL SAAFPSSDTM QLEDIIFRWQ DGGAFLKVRY KEFPQDTEAV 120
  121 SEHVRESFRK RPVRTILHPF STPIPHMVHG IPWLQDLYIF PSRTVDVNFE GPPLSQERLY 180
  181 SIFRTYGKLR SVTINSPTSA TLSFSSLRSA TSALNCMHGF VYGKTEFHMR YRHMNRFVAF 240
  241 KDWLFSHPRF TIPLVAAAIT VLTASLFDPI RKFFVETNIV HGQKLRNINV VGWVKKKTRD 300
  301 IVLSPFHENG TNIKAPIWTT REKDCEQLKE WLDEAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.39794
Match: 2ghpA
Description: No description for 2ghpA was found.

Predicted functions:

Term Confidence Notes
binding 3.06679562635705 bayes_pls_golite062009
nucleic acid binding 1.76055303585115 bayes_pls_golite062009
protein binding 1.32954276279597 bayes_pls_golite062009
RNA binding 1.18157050902203 bayes_pls_golite062009
mRNA binding 0.487879052146416 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [337-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSFIVVQGPR GSGKRDLVDR VVKERKNVLF FDCDRLFSTT NTEMFVSTLA SQTGYFPLFS  60
   61 FLNNISSLID MAAQGLIGQK TGIVSSSEGQ VRQILNTTQT VLRSLALREH KEADTSVLDE 120
  121 SEFLEVHADR LPVVILDNFQ LRKLSNPMQR VVAEWAGNLV KEGIAHVLML TPDVGGTKSL 180
  181 EQYVNGWENR TLLLGDADPV LAQRYVIESL PEEMQTEELR KELRVQLPKI GGRLRDLDYV 240
  241 ARRLRVNSSS VSEAIGGIVS QNASDILQTF LRPASLTSEE KPTFTPEESW TLITYLSQHE 300
  301 YIPYHMLMLD PLFKGHDDAV RALEESELIT ITTVNARPDK VYA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 2fnaA
Description: Crystal structure of (13814777) from SULFOLOBUS SOLFATARICUS at 2.00 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.00435458244286 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.60867879098268 bayes_pls_golite062009
pyrophosphatase activity 1.54036876924203 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.5218662658682 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.51917437681292 bayes_pls_golite062009
hydrolase activity 0.637958076892156 bayes_pls_golite062009
protein binding 0.409258528033042 bayes_pls_golite062009
catalytic activity 0.400036839701206 bayes_pls_golite062009
motor activity 0.294261683163235 bayes_pls_golite062009
purine nucleotide binding 0.15435325982346 bayes_pls_golite062009
nucleotide binding 0.153440379095025 bayes_pls_golite062009
purine ribonucleotide binding 0.130523976113733 bayes_pls_golite062009
ribonucleotide binding 0.130518519278213 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [680-773]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKPVYVTAFR QLVNDPVLSA NMQLVRCNAL IGMANNAIKN DEQELQMLKD LGNLESGVKD  60
   61 RAHYLTTRIQ KNQGVITDNE KSIERLTEAL KKID

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.888 0.038 mitochondrial genome maintenance a.24.14 FAT domain of focal adhesion kinase


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle