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View Structure Prediction Details

Protein: png2
Organism: Schizosaccharomyces pombe
Length: 305 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for png2.

Description E-value Query
Range
Subject
Range
gi|94733520, gi|... - gi|94733520|emb|CAK04218.1| novel protein similar to vertebrate inhibitor of growth family, member 4...
174.0 [0..11] [301..6]
tr|G3GUN3|G3GUN3... - Inhibitor of growth protein OS=Cricetulus griseus GN=I79_001399 PE=3 SV=1
gi|26341284, gi|... - gi|26341284|dbj|BAC34304.1| unnamed protein product [Mus musculus], gi|19111152|ref|NP_579923.1| inh...
174.0 [0..11] [301..6]
gi|55236213, gi|... - gi|58392143|ref|XP_319132.2| ENSANGP00000011912 [Anopheles gambiae str. PEST], gi|55236213|gb|EAA140...
173.0 [0..6] [301..1]
gi|66267465, gi|... - gi|66267465|gb|AAH95434.1| Inhibitor of growth family, member 4 [Homo sapiens], gi|38201670|ref|NP_0...
173.0 [0..11] [301..6]
gi|108879358, gi... - gi|157108206|ref|XP_001650123.1| Inhibitor of growth proteining, ing4 [Aedes aegypti], gi|108879358|...
170.0 [0..6] [301..1]
gi|62648155, gi|... - gi|62648155|ref|XP_216265.3| PREDICTED: similar to Inhibitor of growth protein 4 (p29ING4) [Rattus n...
170.0 [0..11] [301..6]
gi|114643145 - gi|114643145|ref|XP_001169091.1| PREDICTED: inhibitor of growth family, member 4 [Pan troglodytes]
170.0 [0..11] [301..6]

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Predicted Domain #1
Region A:
Residues: [1-209]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTSGIEIFA ALNDFTDAIV SVPESVCGKF TSLKEIDAQV RDIRQNVIQE IGVVLKNEKN  60
   61 DELSGEERCE RLQKTLKEIL PYSDSKICLA TDAMNNIKSC IDRLDAGFEY VELEIPQQLR 120
  121 LGYPDDRALM NYHSTVTPQT SERRRETRRH QNNQHSQQYS SQERSSSYNN FEDASSPQSS 180
  181 YHTPTKRRKN AVPRKSSSPP LSSTKHAPQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [210-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STERRPVRRS ESRLKQTNGE PLVKHDTLDS SDISREGEQL YCYCQQVSYG QMIGCDNENC  60
   61 KREWFHLPCV GLVEPPKGIW YCKECEELAK SSESRQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 1weuA
Description: Solution structure of PHD domain in ING1-like protein BAC25009
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein deacetylase activity 7.50578521120904 bayes_pls_golite062009
histone deacetylase activity 7.35162059871663 bayes_pls_golite062009
histone acetyltransferase activity 7.10262960897544 bayes_pls_golite062009
lysine N-acetyltransferase activity 7.10262960897544 bayes_pls_golite062009
deacetylase activity 6.55925777139018 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5.24378850198774 bayes_pls_golite062009
N-acetyltransferase activity 5.0952093808777 bayes_pls_golite062009
4.93977737347339 bayes_pls_golite062009
4.75659254650148 bayes_pls_golite062009
N-acyltransferase activity 4.73470737654883 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4.39452339322141 bayes_pls_golite062009
acetyltransferase activity 4.29938591960121 bayes_pls_golite062009
methylated histone residue binding 4.19057851212315 bayes_pls_golite062009
acyltransferase activity 3.59302841227183 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.54892905221507 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.34035867339622 bayes_pls_golite062009
histone binding 3.01402804224903 bayes_pls_golite062009
binding 2.78627791259335 bayes_pls_golite062009
nucleosome binding 1.69494047037058 bayes_pls_golite062009
protein binding 1.6308789519356 bayes_pls_golite062009
chromatin binding 1.0360039180364 bayes_pls_golite062009
nucleic acid binding 1.01735624308761 bayes_pls_golite062009
DNA binding 0.896491359501813 bayes_pls_golite062009
transcription regulator activity 0.723245820583374 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.655033722565177 bayes_pls_golite062009
kinase activity 0.596989785523293 bayes_pls_golite062009
histone methyltransferase activity 0.476506467104495 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.465950484314184 bayes_pls_golite062009
protein kinase activity 0.405766438875014 bayes_pls_golite062009
cytoskeletal protein binding 0.327424740985033 bayes_pls_golite062009
transferase activity 0.245705939593188 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 0.0490968711985191 bayes_pls_golite062009
histone acetyl-lysine binding 0.0410393640547611 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle