YRC Public Data Repository - Protein Structure Prediction

Protein:	ret2
Organism:	Schizosaccharomyces pombe
Length:	240 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ret2.

Description	E-value	Query Range	Subject Range
gi\|42554497, gi\|... - gi\|46130854\|ref\|XP_389158.1\| hypothetical protein FG08982.1 [Gibberella zeae PH-1], gi\|42554497\|gb\|E...	251.0	[0..2]	[230..1]
gi\|28949965 - gi\|28949965\|emb\|CAD70726.1\| probable clathrin assembly protein AP47 [Neurospora crassa]	249.0	[0..2]	[230..1]
gi\|119183349, gi... - gi\|90301509\|gb\|EAS31140.1\| hypothetical protein CIMG_06619 [Coccidioides immitis RS], gi\|119183349\|r...	249.0	[0..2]	[230..1]
gi\|78191071 - gi\|78191071\|gb\|ABB29860.1\| AP-1 mu subunit [Cryphonectria parasitica]	247.0	[0..2]	[230..1]
gi\|70997882, gi\|... - gi\|70997882\|ref\|XP_753673.1\| AP-1 adaptor complex subunit mu [Aspergillus fumigatus Af293], gi\|66851... gi\|159126594 - gi\|159126594\|gb\|EDP51710.1\| AP-1 adaptor complex subunit mu, putative [Aspergillus fumigatus A1163]	246.0	[0..2]	[230..1]
gi\|111060420, gi... - gi\|169615757\|ref\|XP_001801294.1\| hypothetical protein SNOG_11041 [Phaeosphaeria nodorum SN15], gi\|11...	246.0	[0..2]	[230..1]
gi\|114191326, gi... - gi\|115400143\|ref\|XP_001215660.1\| AP-1 complex subunit mu-1 [Aspergillus terreus NIH2624], gi\|1141913...	245.0	[0..2]	[230..1]
gi\|12000357 - gi\|12000357\|gb\|AAG11391.1\| clathrin-adaptor medium chain apm 1 [Dictyostelium discoideum]	244.0	[0..1]	[230..1]
gi\|50752367 - gi\|50752367\|ref\|XP_422757.1\| PREDICTED: similar to hypothetical protein FLJ11198 [Gallus gallus]	243.0	[0..2]	[238..1]
gi\|60464684, gi\|... - gi\|66805039\|ref\|XP_636252.1\| clathrin-adaptor medium chain apm1 [Dictyostelium discoideum AX4], gi\|6... AP1M_DICDI - AP-1 complex subunit mu OS=Dictyostelium discoideum GN=apm1 PE=1 SV=1	243.0	[0..1]	[230..1]

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Predicted Domain #1

Region A:
Residues: [1-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVLAVSIVN RGGKAIISRQ FREMSRVRVE SLLSSFPALV SEKSQNTTVE SDNVRFVYQP  60
   61 LDELYIVLIT NLQSNILQDI DTLHLLSQVV TSICSSLEER EILEYAFEIF TAFDEATSLG 120
  121 YRDNVSLTQI KTYLEMESHE EKIQEIVSRN KEIEATEERK RRIKQLELQK KEAARRAAQN 180
  181 LPSADAYESI GYQTVNTTFA TSNVEDESAM ESYHAAAKAS SAPKAKGMQL GKKKNTSLLY 240
  241

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.0
Match:	1gw5M
Description:	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; Mu2 adaptin (clathrin coat assembly protein AP50)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
clathrin binding	3.29076846857007	bayes_pls_golite062009
SNAP receptor activity	2.23518960752054	bayes_pls_golite062009
protein transporter activity	2.04806587835812	bayes_pls_golite062009
transporter activity	1.71943098913274	bayes_pls_golite062009
binding	1.51276821555775	bayes_pls_golite062009
signal recognition particle binding	1.21465932013369	bayes_pls_golite062009
protein binding	1.08917223347521	bayes_pls_golite062009
protein-cysteine S-palmitoleyltransferase activity	1.07022749554273	bayes_pls_golite062009
protein-cysteine S-acyltransferase activity	1.07022749554273	bayes_pls_golite062009
substrate-specific transporter activity	0.939682472116899	bayes_pls_golite062009
palmitoyltransferase activity	0.76687594030379	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.131410992694836	bayes_pls_golite062009
pyrophosphatase activity	0.0936690070284361	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.0846345824909659	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0820309452260982	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: