YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC569.07
Organism:	Schizosaccharomyces pombe
Length:	470 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC569.07.

Description	E-value	Query Range	Subject Range
AATR2_SCHPO - Aromatic amino acid aminotransferase C1773.13 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)... SPBC1773.13 - aromatic aminotransferase	267.0	[0..6]	[470..6]
gi\|196253921, gi... - gi\|196253921\|ref\|ZP_03152522.1\| aminotransferase class I and II [Clostridium thermocellum DSM 4150],... gi\|67849411, gi\|... - gi\|67916633\|ref\|ZP_00510335.1\| Aminotransferase, class I and II [Clostridium thermocellum ATCC 27405...	262.0	[0..55]	[464..22]
AAT_AQUAE - Aspartate aminotransferase OS=Aquifex aeolicus (strain VF5) GN=aspC PE=3 SV=1 AAT_AQUAE - Aspartate aminotransferase OS=Aquifex aeolicus GN=aspC PE=3 SV=1	261.0	[0..61]	[466..30]
gi\|18976493, gi\|... - gi\|18976493\|ref\|NP_577850.1\| putative aspartate aminotransferase [Pyrococcus furiosus DSM 3638], gi\|...	258.0	[0..90]	[466..73]
gi\|48895332, gi\|... - gi\|71675283\|ref\|ZP_00673028.1\| Aminotransferase, class I and II [Trichodesmium erythraeum IMS101], g...	258.0	[0..55]	[465..22]
gi\|118477096, gi... - gi\|118477096\|ref\|YP_894247.1\| aspartate aminotransferase [Bacillus thuringiensis str. Al Hakam], gi\|... gi\|167531298, gi... - gi\|167633260\|ref\|ZP_02391585.1\| aspartate aminotransferase [Bacillus anthracis str. A0442], gi\|16753... gi\|164714877, gi... - gi\|165869437\|ref\|ZP_02214096.1\| aspartate aminotransferase [Bacillus anthracis str. A0488], gi\|16471... gi\|225786881, gi... - gi\|225863508\|ref\|YP_002748886.1\| aspartate aminotransferase [Bacillus cereus 03BB102], gi\|225786881\|... gi\|227003591, gi... - gi\|227815608\|ref\|YP_002815617.1\| aspartate aminotransferase [Bacillus anthracis str. CDC 684], gi\|22... gi\|228914220, gi... - gi\|228914220\|ref\|ZP_04077836.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar pulsiensi... gi\|228833051, gi... - gi\|228926675\|ref\|ZP_04089744.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar pondicher... gi\|228826736, gi... - gi\|228932933\|ref\|ZP_04095798.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar andalousi... gi\|228814479, gi... - gi\|228945244\|ref\|ZP_04107600.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar monterrey... gi\|228662306, gi... - gi\|229121187\|ref\|ZP_04250424.1\| Aspartate aminotransferase [Bacillus cereus 95/8201], gi\|228662306\|g... gi\|228599688, gi... - gi\|229183839\|ref\|ZP_04311056.1\| Aspartate aminotransferase [Bacillus cereus BGSC 6E1], gi\|228599688\|... gi\|229266533, gi... - gi\|229602125\|ref\|YP_002866048.1\| aspartate aminotransferase [Bacillus anthracis str. A0248], gi\|2292... gi\|254723720 - gi\|254723720\|ref\|ZP_05185506.1\| aspartate aminotransferase [Bacillus anthracis str. A1055] gi\|254734481 - gi\|254734481\|ref\|ZP_05192193.1\| aspartate aminotransferase [Bacillus anthracis str. Western North Am... gi\|254740892 - gi\|254740892\|ref\|ZP_05198580.1\| aspartate aminotransferase [Bacillus anthracis str. Kruger B] gi\|170128600, gi... - gi\|170706502\|ref\|ZP_02896962.1\| aspartate aminotransferase [Bacillus anthracis str. A0389], gi\|17012... gi\|254755131 - gi\|254755131\|ref\|ZP_05207165.1\| aspartate aminotransferase [Bacillus anthracis str. Vollum] gi\|167639102, gi... - gi\|167639102\|ref\|ZP_02397375.1\| aspartate aminotransferase [Bacillus anthracis str. A0193], gi\|16751... gi\|254759668 - gi\|254759668\|ref\|ZP_05211692.1\| aspartate aminotransferase [Bacillus anthracis str. Australia 94] gi\|190568685, gi... - gi\|190568685\|ref\|ZP_03021590.1\| aspartate aminotransferase [Bacillus anthracis Tsiankovskii-I], gi\|1... gi\|172083508, gi... - gi\|177650364\|ref\|ZP_02933331.1\| aspartate aminotransferase [Bacillus anthracis str. A0174], gi\|17208... gi\|196030164, gi... - gi\|196039019\|ref\|ZP_03106326.1\| aspartate aminotransferase [Bacillus cereus NVH0597-99], gi\|19603016... gi\|195993859, gi... - gi\|196033425\|ref\|ZP_03100837.1\| aspartate aminotransferase [Bacillus cereus W], gi\|195993859\|gb\|EDX5... gi\|218902756, gi... - gi\|218902756\|ref\|YP_002450590.1\| aspartate aminotransferase [Bacillus cereus AH820], gi\|218539609\|gb... gi\|196046666, gi... - gi\|196046666\|ref\|ZP_03113890.1\| aspartate aminotransferase [Bacillus cereus 03BB108], gi\|196022599\|g... gi\|49332551, gi\|... - gi\|49480995\|ref\|YP_035760.1\| aspartate aminotransferase [Bacillus thuringiensis serovar konkukian st... gi\|52143804, gi\|... - gi\|52143804\|ref\|YP_083024.1\| aspartate aminotransferase [Bacillus cereus E33L], gi\|51977273\|gb\|AAU18... gi\|50082989, gi\|... - gi\|50196927\|ref\|YP_052621.1\| aspartate aminotransferase [Bacillus anthracis str. 'Ames Ancestor'], g... gi\|49184471, gi\|... - gi\|49184471\|ref\|YP_027723.1\| aspartate aminotransferase [Bacillus anthracis str. Sterne], gi\|4917839... gi\|21399462, gi\|... - gi\|65318911\|ref\|ZP_00391870.1\| COG0436: Aspartate/tyrosine/aromatic aminotransferase [Bacillus anthr... gi\|30255869, gi\|... - gi\|30261641\|ref\|NP_844018.1\| aspartate aminotransferase [Bacillus anthracis str. Ames], gi\|30255869\|...	258.0	[0..62]	[465..29]
gi\|14520410, gi\|... - gi\|5457625\|emb\|CAB49116.1\| Multiple substrate aminotransferase [Pyrococcus abyssi GE5], gi\|14520410\|... gi\|5457625, gi\|7... - pir\|\|E75208 probable valine-pyruvate transaminase (EC 2.6.1.66) PAB2227 [similarity] - Pyrococcus ab...	258.0	[0..90]	[466..69]
AAT1_BACSU - Aspartate aminotransferase OS=Bacillus subtilis GN=aspB PE=3 SV=1 AAT1_BACSU - Aspartate aminotransferase OS=Bacillus subtilis (strain 168) GN=aspB PE=3 SV=1 gi\|221314475 - gi\|221314475\|ref\|ZP_03596280.1\| aspartate aminotransferase [Bacillus subtilis subsp. subtilis str. N... gi\|221319397 - gi\|221319397\|ref\|ZP_03600691.1\| aspartate aminotransferase [Bacillus subtilis subsp. subtilis str. J... gi\|221323673 - gi\|221323673\|ref\|ZP_03604967.1\| aspartate aminotransferase [Bacillus subtilis subsp. subtilis str. S...	258.0	[0..61]	[467..28]
gi\|228984724, gi... - gi\|228984724\|ref\|ZP_04144896.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar tochigien... gi\|228628337, gi... - gi\|229155210\|ref\|ZP_04283322.1\| Aspartate aminotransferase [Bacillus cereus ATCC 4342], gi\|228628337... gi\|47566009, gi\|... - gi\|47566009\|ref\|ZP_00237047.1\| aspartate aminotransferase [Bacillus cereus G9241], gi\|47556926\|gb\|EA...	257.0	[0..62]	[465..29]

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Predicted Domain #1

Region A:
Residues: [1-60]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNLKKKYQH HLSLESASRE YGPFQMLGRI QSDSDIKMLS FAGGEPNPSK FPIHKLSVSF  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.58
Match:	1x0mA
Description:	a Human Kynurenine Aminotransferase II Homologue from Pyrococcus horikoshii OT3
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [61-470]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEVNSWEKDT NKDATVSYEL SNNANEGSLD LLGALQYGQC QGIPELVKFI KDHVGQIHMP  60
   61 QYKDWDIKIT NGNTIGLEYC LRLLVNRGDC ILIEKYTYPA AITAMRPLGV KFIPIDMDEN 120
  121 GMLPESFEKV METWDSSLGA RPHVLYTIPT GQNPTGSTLT LERRKKFLTL AKKYDIIIVE 180
  181 DEPYYFLQME KYDANWKPDK QAFNISSFKK KLIPSLLHLD TDGRVLRVDS FSKLIVPGLR 240
  241 LGWITGNSLF IDRITRYAEV CTESPSGVSQ VVLYAILNRW GQNGFLEWLQ DLQNSYTMRR 300
  301 NALLLAADKH LPKSVCKYHS PKAGLFLWVE LDKNRLICSN MDKSISEIEM EIFVELVNNG 360
  361 VKPVCGQLFM GEPNSADKIF FRFAYSLADL STFEAGLERF TSTIQKYFQL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.154902
Match:	1x0mA
Description:	a Human Kynurenine Aminotransferase II Homologue from Pyrococcus horikoshii OT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-aminobutyrate transaminase activity	2.50008459801306	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
transcription regulator activity	2.08143587519879	bayes_pls_golite062009
DNA binding	1.80954597626789	bayes_pls_golite062009
nucleic acid binding	1.80201988288625	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	1.63055151623667	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	1.63055151623667	bayes_pls_golite062009
transcription factor activity	1.4411091720163	bayes_pls_golite062009
transferase activity	1.44093490824786	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
kynureninase activity	1.27354164393136	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
binding	1.09053123792737	bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances	0.942545094747784	bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds	0.845816961387768	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	0.619695949258279	bayes_pls_golite062009
5-aminolevulinate synthase activity	0.54326874956263	bayes_pls_golite062009
structural molecule activity	0.347975812448725	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
aromatic-amino-acid:2-oxoglutarate aminotransferase activity	0.0916183433120769	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: