| Protein: | fkh2 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 642 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fkh2.
| Description | E-value | Query Range |
Subject Range |
|
|
190.0 | [0..74] | [553..7] |
|
|
183.0 | [0..208] | [473..128] |
|
|
183.0 | [0..205] | [472..95] |
|
|
178.0 | [0..9] | [178..287] |
|
|
178.0 | [0..9] | [178..261] |
|
|
178.0 | [0..9] | [178..274] |
|
|
177.0 | [0..76] | [619..10] |
|
|
175.0 | [0..232] | [611..1490] |
|
Region A: Residues: [1-210] |
1 11 21 31 41 51
| | | | | |
1 MTVRRLESKS EHISDDEERK EQLDYKKQMD VDTDRNIVLN GRLESQIAKL SVPPHEMRVV 60
61 DDYSNSKNAE RHSGEIQAYA KFAGSTWTYY VKKIRIILGR EPANPSPKGK NEDLEVIDMN 120
121 FGPSKVVSRK HAVVEYDLDD QTWNCSVYGR NGIKVDGKLF KNGETVKLTS GSILEVAGLQ 180
181 MMFVLPNAAE QKQTDESTIK EDAIKSEISA
|
| Detection Method: |  |
| Confidence: | 4.31 |
| Match: | 1g3gA |
| Description: | Phosphotyrosine binding domain of Rad53 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.49130250684713 | bayes_pls_golite062009 |
| transcription regulator activity | 3.38780975952028 | bayes_pls_golite062009 |
| DNA binding | 3.17754626214699 | bayes_pls_golite062009 |
| nucleic acid binding | 3.1171915055278 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, cytoplasmic mediator activity | 2.46194647885285 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase signaling protein activity | 2.25215920371602 | bayes_pls_golite062009 |
| protein binding | 2.20369144716037 | bayes_pls_golite062009 |
| transcription factor activity | 2.00503872581265 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.58636372907213 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity | 1.55291063824788 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.50718172248835 | bayes_pls_golite062009 |
| transcription activator activity | 1.45614128243985 | bayes_pls_golite062009 |
| R-SMAD binding | 1.42136232818793 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.31247181538194 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.0211816353095 | bayes_pls_golite062009 |
| promoter binding | 0.986206497817435 | bayes_pls_golite062009 |
| transcription factor binding | 0.840886266060694 | bayes_pls_golite062009 |
| histone binding | 0.719484498280197 | bayes_pls_golite062009 |
| chromatin binding | 0.599108072971618 | bayes_pls_golite062009 |
| SMAD binding | 0.465937265607219 | bayes_pls_golite062009 |
| co-SMAD binding | 0.417372097853037 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.196567610974905 | bayes_pls_golite062009 |
| transcription repressor activity | 0.0741267027726338 | bayes_pls_golite062009 |
|
Region A: Residues: [211-331] |
1 11 21 31 41 51
| | | | | |
1 AVNDAAEYGD NKKPPYSYSV MIAQAILSSS ECMMTLSNIY SWISTHYPYY RTTKSGWQNS 60
61 IRHNLSLNKA FRKVPRKSGE QGKGMKWSIV PEFREEFIAK TRKTPRKRSP SSPVPLLAKK 120
121 R
|
| Detection Method: | |
| Confidence: | 41.522879 |
| Match: | 1d5vA |
| Description: | Adipocyte-transcription factor FREAC-11 (s12, fkh-14) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.55329976718261 | bayes_pls_golite062009 |
| DNA binding | 5.08959163553491 | bayes_pls_golite062009 |
| nucleic acid binding | 4.99681957904233 | bayes_pls_golite062009 |
| transcription factor activity | 4.33152142980289 | bayes_pls_golite062009 |
| binding | 3.52874320222492 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.48053910222825 | bayes_pls_golite062009 |
| transcription activator activity | 2.37668609508629 | bayes_pls_golite062009 |
| transcription repressor activity | 2.22485867684613 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.70025468248325 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.893172944075433 | bayes_pls_golite062009 |
| transcription factor binding | 0.85714789329232 | bayes_pls_golite062009 |
| protein binding | 0.753698599635855 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.461477365615935 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.0856082199488197 | bayes_pls_golite062009 |
|
Region A: Residues: [332-469] |
1 11 21 31 41 51
| | | | | |
1 EGSPSLPIPI LPKMKDTSIP AAEPASSTTS ARDQTPSTPK DVGSPSTAET SAEEKQMETY 60
61 KTPTHAALSD IISTHDYALD ANSASQTKKA AFGSPIGSST YPTSSPAPFW KYVAVPNPHD 120
121 WPQVGSYDTI SPYRNPVN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [470-642] |
1 11 21 31 41 51
| | | | | |
1 SHLIYSQIQQ SSPKKIDEQL HDLQGVDLVN GFEGISSWRE SMVNKLRSSV SDSPTMNLAN 60
61 SNSKSSPVAV QRVSTLPQAS ANKQAKEMES KMSNSPTQKS KTEENNQAVR AILDASATME 120
121 KQYDLHRLPT PTSQTESASV PQIANPPNSQ NLVKEKSPQQ YIQVPQSNVK SSA
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
