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View Structure Prediction Details

Protein: bpb1
Organism: Schizosaccharomyces pombe
Length: 587 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bpb1.

Description E-value Query
Range
Subject
Range
POL_HV1RH - Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) GN=ga...
420.0 [0..44] [449..90]
gi|19072104 - gi|19072104|dbj|BAB85751.1| Gag-pol fusion polyprotein [Human immunodeficiency virus 1]
419.0 [0..45] [453..91]
POL_HV1B9 - Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype B (strain 89.6) GN=gag-po...
416.0 [0..44] [453..90]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNSRSVGST GSNNTPLGRR RFDEKPDSLP PLPDANGMSN GYRDSYKSNS RMDHRPDGYH  60
   61 DGRGRRAYRK HYWGHPTPIE EM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [83-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSQMELETA VKSCMTMEQL ELYSLNVRLE EITQKLRTGD VVPHHRERSP SPPPQYDNHG  60
   61 RRLNTREIRY KKKLEDERHR IIERAMKMVP GFRAPSDYRR PAKTQEKVYV PVKDYPEINF 120
  121 IGLLIGPRGH TLKDMEAKSG AKIAIRGKGS VKEGKGRSDP S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.154902
Match: 1e6jP
Description: HIV capsid protein, dimerisation domain; HIV-1 capsid protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.89697146569581 bayes_pls_golite062009
protein binding 1.56588389135086 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [244-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VRGNMEEDLH CLVTADSEDK INHAIKLIDN VIQTAASVPE GQNDLKRNQL RQLATLNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.39794
Match: 1k1gA
Description: RNA splicing factor 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.76415077523249 bayes_pls_golite062009
mRNA binding 5.07455187994216 bayes_pls_golite062009
4.82131641133915 bayes_pls_golite062009
nucleic acid binding 4.28581120742478 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
protein binding 2.21586499514642 bayes_pls_golite062009
poly-pyrimidine tract binding 2.05765562493656 bayes_pls_golite062009
transcription regulator activity 2.01194399592256 bayes_pls_golite062009
DNA binding 1.78469836520678 bayes_pls_golite062009
single-stranded RNA binding 0.981003625136521 bayes_pls_golite062009
transcription factor activity 0.866815968834173 bayes_pls_golite062009
transcription repressor activity 0.594072241231183 bayes_pls_golite062009
mRNA 3'-UTR binding 0.489176583045793 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
transcription activator activity 0.210494225017032 bayes_pls_golite062009
transcription factor binding 0.139588254197875 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [302-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLRDDENQVC QNCGNVGHRR FDCPERINHT MNIVCRHCGS IGHIARDCPV RDQQPPMADS  60
   61 TADREYQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.0
Match: 1a1tA
Description: HIV nucleocapsid
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [369-513]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLMQELGGGS AISNGNGEPQ KSIEFSESGA ASPQAGHPPP WAAASTSVSS STSSPAPWAK  60
   61 PASSAAPSNP APWQQPAAPQ SAPALSMNPS SLPPWQQPTQ QSAVQPSNLV PSQNAPFIPG 120
  121 TSAPLPPTTF APPGVPLPPI PGAPG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.13
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #6
Region A:
Residues: [514-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNLNMSQPP MVPPGMALPP GMPAPFPGYP AVPAMPGIPG ATAPPGAPGS YNTSESSNLN  60
   61 APPGVSMPNG YSNR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.8
Match: 1wckA
Description: Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle