| Protein: | thi5 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 857 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for thi5.
| Description | E-value | Query Range |
Subject Range |
|
|
235.0 | [0..30] | [857..6] |
|
|
219.0 | [0..299] | [856..225] |
|
|
216.0 | [0..3] | [854..45] |
|
|
214.0 | [0..1] | [799..1] |
|
|
213.0 | [0..218] | [857..154] |
|
|
213.0 | [0..26] | [846..57] |
|
|
208.0 | [0..297] | [827..208] |
|
Region A: Residues: [1-97] |
1 11 21 31 41 51
| | | | | |
1 MCPSDFSSRS LFLEAKEEEY KQRRRVPLDS RRRVRRACLS CRAKKIRCSG SEPCQACIAT 60
61 PSQCKYADSL KERTPSKQFI AELSQRQKCF EYLMELL
|
| Detection Method: |  |
| Confidence: | 6.522879 |
| Match: | 1zmeC |
| Description: | PUT3 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.56444258780502 | bayes_pls_golite062009 |
| DNA binding | 4.26146437716972 | bayes_pls_golite062009 |
| nucleic acid binding | 4.17369933547911 | bayes_pls_golite062009 |
| transcription factor activity | 3.049435548132 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.98081393153291 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.93914501897006 | bayes_pls_golite062009 |
| binding | 2.91929847152301 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 2.44382866473054 | bayes_pls_golite062009 |
| transcription activator activity | 2.24483536326713 | bayes_pls_golite062009 |
|
Region A: Residues: [98-256] |
1 11 21 31 41 51
| | | | | |
1 CPSLPHDTRS LVKLCKHVES SLASGSDVRS LLIPGSIDQS VLKVAATNNK DDSSAVKSAN 60
61 VSFPSSSTPP SSDSNFSSIQ NTDLNTSIKF TENISANAIH VNQDKVIRSA NNLIINSQPI 120
121 LPVRSFLDAL GEPIYLSPTS STYFLNSVLA SLQLNSSNT
|
| Detection Method: | |
| Confidence: | 2.32 |
| Match: | 1pyiA |
| Description: | PPR1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.34861813464065 | bayes_pls_golite062009 |
| DNA binding | 4.03985756894684 | bayes_pls_golite062009 |
| nucleic acid binding | 3.97978190843512 | bayes_pls_golite062009 |
| transcription factor activity | 2.87348461329489 | bayes_pls_golite062009 |
| binding | 2.82809978070212 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.77469997789536 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.70904317608141 | bayes_pls_golite062009 |
| transcription activator activity | 2.1512787242583 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 2.08956709478484 | bayes_pls_golite062009 |
|
Region A: Residues: [257-349] |
1 11 21 31 41 51
| | | | | |
1 PESLLIDYQS KIPEDLSSSL LPLELNTLQS TPTSVSVGSA SSQGTHEYSI INLTSNHSSF 60
61 SLKALKKIAH NLLPPVSVAE RYANEFFLRY QSF
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.594 | 0.021 | thiamin biosynthetic process | a.3.1 | Cytochrome c |
| View | Download | 0.590 | 0.021 | thiamin biosynthetic process | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.823 | 0.021 | thiamin biosynthetic process | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.584 | 0.021 | thiamin biosynthetic process | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.631 | 0.021 | thiamin biosynthetic process | a.112.1 | Description not found. |
|
Region A: Residues: [350-522] |
1 11 21 31 41 51
| | | | | |
1 FYFYPPSVFS NRYQILADGL VNSDTLDTGF LAVALLIVVL GHFSNNNINV LPKEVQLSHI 60
61 DSMIQISEQL ISSLLNRCTL SSIQAVFLLS LYHFLTGNFK CAYSYLGFAI HSAHTLGLEH 120
121 GSTDNSTLNE VSTEETSIRI CWSLRVLASF LYIQSGITPI INLFPNGLNS LKL
|
| Detection Method: | |
| Confidence: | 19.0 |
| Match: | PF04082.9 |
| Description: | No description for PF04082.9 was found. |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.473 | 0.224 | regulation of transcription from RNA polymerase II promoter | a.74.1 | Cyclin-like |
| View | Download | 0.723 | 0.062 | thiamin biosynthetic process | a.47.2 | t-snare proteins |
| View | Download | 0.476 | 0.020 | thiamin biosynthetic process | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.511 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.477 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
|
Region A: Residues: [523-606] |
1 11 21 31 41 51
| | | | | |
1 PTVVPELEAR HLPSSVFHFV AIIKYAEISV RSLNSLYESS SDYLMDVSNF PKLLLKVERI 60
61 YSQARNWKLN LTHQQLNGTN DTSD
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [607-857] |
1 11 21 31 41 51
| | | | | |
1 LLFHSNVSLH LFYHYLIVKV SCPIMFFYLN NWYSVKPSSF TKGLNNKPSL EDVFSNLETC 60
61 YESAKAIVQL SSKLLSAGQM DKCFYLEFEI LYCSAIVLFL FSVMHLGAEN PLLESIYLLE 120
121 DMGSRTIDSK VRLEKLKSAI EIFDINSATE MPINEPLSAS FESVNKENSQ SGYMAWQNWV 180
181 TELSSSNIPL GHALGNPESN NSSNSFKPSH PSQSFLVNES LDFSSNPKEP PFLPWSEALL 240
241 NMDMQLNRLG P
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
