YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC887.02
Organism:	Schizosaccharomyces pombe
Length:	667 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC887.02.

Description	E-value	Query Range	Subject Range
gi\|50745842 - gi\|50745842\|ref\|XP_420265.1\| PREDICTED: similar to chloride channel CLC-5 [Gallus gallus]	447.0	[0..2]	[664..927]
CLCN3_RAT - H(+)/Cl(-) exchange transporter 3 OS=Rattus norvegicus GN=Clcn3 PE=2 SV=2	439.0	[0..3]	[664..87]
gi\|74177944, gi\|... - gi\|74177944\|dbj\|BAE29767.1\| unnamed protein product [Mus musculus], gi\|74141979\|dbj\|BAE41053.1\| unna...	438.0	[0..3]	[664..87]
CLCN3_RABIT - H(+)/Cl(-) exchange transporter 3 OS=Oryctolagus cuniculus GN=CLCN3 PE=2 SV=3 CLCN3 - chloride channel 3 gi\|114596820, gi... - gi\|114596820\|ref\|XP_001153970.1\| PREDICTED: chloride channel 3 isoform 5 [Pan troglodytes], gi\|11459...	438.0	[0..3]	[664..87]
gi\|220061722, gi... - gi\|47210785\|emb\|CAF91095.1\| unnamed protein product [Tetraodon nigroviridis], gi\|220061722\|gb\|ACL795...	437.0	[0..3]	[664..64]
gi\|70561322 - gi\|70561322\|emb\|CAJ14974.1\| chloride channel 3 [Canis lupus familiaris]	436.0	[0..3]	[664..60]

Back

Predicted Domain #1

Region A:
Residues: [1-492]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDDQLIDWI HERYEEQKSA NRLAGRFRFL GLETKYSIIS IISGIFIGLT AALLNALASL  60
   61 LNSFREGYCT VNILFDKQTC CSTLTEDYEC QEFFFWRNNH SVFVSCLIYV SVSVGFAFIA 120
  121 TTLGYVVAPA ARASGIPTIK AILSGYKYPD MNVFFSIKTL CSKSLAVCFS VASGLWVGKE 180
  181 GPFVHIATNI IYLVERIAPS LADSEIFTRQ LLAAAMASGI AASFNAPVGG VIFALEQLAS 240
  241 SSFPSLFTGS IWYEFLCSAS SVVALQLIRS WHTDVGYLSY VSLDRRWSYK DTLPFIFISI 300
  301 LCGCLGSVLI YLNMKFASKT KGFSKISNVF FVIFLSLITS LTAYAILGES ELLFNPMELF 360
  361 PQVINSCSPS SSTVLCETTF WVTAIVLFTS ALLGLLLTSA TFGAAIPTGI IVPSLAIGAC 420
  421 IGRAVGTLLK SRFPSLAGTS IYGVIGSIAF LSSTTRLVVA LVVILFELTG ALNIALPLML 480
  481 ATLISKWVSD SI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.154902
Match:	1kplA
Description:	Clc chloride channel
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
anion channel activity	6.77290758049983	bayes_pls_golite062009
chloride channel activity	6.77290758049983	bayes_pls_golite062009
anion transmembrane transporter activity	6.08111514985329	bayes_pls_golite062009
voltage-gated chloride channel activity	5.99544422864122	bayes_pls_golite062009
voltage-gated anion channel activity	5.99544422864122	bayes_pls_golite062009
ion transmembrane transporter activity	5.07840957725271	bayes_pls_golite062009
ion channel activity	4.93164650815682	bayes_pls_golite062009
substrate-specific channel activity	4.81149777353187	bayes_pls_golite062009
channel activity	4.78965126968592	bayes_pls_golite062009
passive transmembrane transporter activity	4.78965126968592	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.67227438984104	bayes_pls_golite062009
voltage-gated ion channel activity	4.27956097534048	bayes_pls_golite062009
voltage-gated channel activity	4.255638017629	bayes_pls_golite062009
gated channel activity	4.1072949331811	bayes_pls_golite062009
transporter activity	2.94995161862691	bayes_pls_golite062009
transmembrane transporter activity	2.84443650880263	bayes_pls_golite062009
substrate-specific transporter activity	2.82470397063503	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [493-667]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IETSIYDAWI QFRNIPYFPS SNSLKFSIPL NFPVRSPEQL VRLPIRSCSI EELERAMHDS  60
   61 SQSFFVVLKN DTEFFEGFIS RNKVSELLNR RPMSSNMQTT DNTGLDPLRS ASAPVDSTFD 120
  121 LFDYIHPTTF TLNYDTPPVL MLKLFKDAGI TNLALLNHGK LHGVLTKIVC FICTI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.69897
Match:	2ooxG
Description:	No description for 2ooxG was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: