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View Structure Prediction Details

Protein: SPAPB1A10.06c
Organism: Schizosaccharomyces pombe
Length: 1183 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAPB1A10.06c.

Description E-value Query
Range		 Subject
Range
DHX8_MOUSE - ATP-dependent RNA helicase DHX8 OS=Mus musculus GN=Dhx8 PE=2 SV=1
 612.0 [0..45] [1173..257]
gi|73965615 - gi|73965615|ref|XP_537627.2| PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box polypeptide 8 isoform ...
 612.0 [0..45] [1173..229]
gi|76645050 - gi|76645050|ref|XP_616213.2| PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box polypeptide 8, partial...
 611.0 [0..46] [1173..247]
gi|28704113 - gi|28704113|gb|AAH47327.1| DHX8 protein [Homo sapiens]
 610.0 [0..45] [1173..227]
gi|42551260, gi|... - gi|46121247|ref|XP_385178.1| hypothetical protein FG05002.1 [Gibberella zeae PH-1], gi|42551260|gb|E...
 610.0 [0..3] [1170..141]
gi|114145427, gi... - gi|37654286|gb|AAQ96248.1| LRRGT00035 [Rattus norvegicus], gi|114145427|ref|NP_001041309.1| DEAH (As...
 610.0 [0..45] [1159..202]
gi|68370298 - gi|68370298|ref|XP_685860.1| PREDICTED: similar to ATP-dependent helicase DHX8 (RNA helicase HRH1) (...
 610.0 [0..59] [1173..237]

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Predicted Domain #1
Region A:
Residues: [1-65] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRLRKRFNE KGRQSGIQKM LNLKRARLHR SVREQESSSE VHANPEPDNQ DSNAEILIDV  60
   61 PKEER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #2
Region A:
Residues: [66-811] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKRKQELKDQ LLKENEGSIS SKKKKRLDKY IENKLKKEEV ASLIAKLAEE RIDTSLLSSS  60
   61 KNLGKQATAK EKLKKSLLEE KLGLPLSDAD SRLYKVVDVE TTTTKSSTAE TNAPEKYSTR 120
  121 SGFGFGFSTG TNESEITPNI KVLPPKKKKN ASWGKMLNED PEYDSAEEDY LSTDSEEFSE 180
  181 DSDNSSEENK DTNEPSTKDA EKTVPEDVVN LRSEQKLQPS FGHPEFENED FDLETSEDDS 240
  241 SDDATERASR FKSWANKQIL GADVGEKSHD VAPDNKIDNP DADMVRAQRM PRKLKMREED 300
  301 VEPTADDIEI KGRKTTYTII NRPPEIQESR LALPIVAEEQ RIMEQIFAND VVIICGATGS 360
  361 GKTTQLPQFL FEAGFSSPES ENPGMIAITQ PRRVAAVSIA KRVSEELTGF SSKVSYQIRF 420
  421 DSTINPDTAI KFMTDGILLR ELSSDFLLTA YSAVIVDEAH ERSVNTDILL GLLSRIVRLR 480
  481 REMSKSDQKV KPLKLIIMSA TLRVTDFSEN KLLFSVPPPI IKIDARQYPV SIHFNRTTKP 540
  541 DYLQDAFDKV CLIHKRLPAG SILVFLTGQQ EVEQLCQMLR KRFVRSFRPL KSRARIVVSR 600
  601 KTMSVENEDL QSETEDIDQV PTSSSSSVTY DDESEPMYVL PLYSLLTTED QMKVFDSSPE 660
  661 GHRMCIVATN VAETSITIPN IRYVVDCGKA KERVYNEKTS VQKFEVRWIS KANADQRAGR 720
  721 AGRTGPGHCY RLYSSAVFDS SFPLHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.39794
Match: 1gm5A
Description: RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
4.704140727858 bayes_pls_golite062009
binding 2.44689197844883 bayes_pls_golite062009
RNA binding 2.29590582680214 bayes_pls_golite062009
structural constituent of ribosome 1.57653963868443 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
nucleic acid binding 1.41477043612798 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 1.35850109411274 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 1.35845277283398 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 1.35845277283398 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.15212468568198 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
exoribonuclease activity 1.10445667068538 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.83268201349295 bayes_pls_golite062009
mRNA binding 0.76699944561918 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
motor activity 0.61636596887462 bayes_pls_golite062009
structural molecule activity 0.596382945962261 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.461763181659193 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.458831409927227 bayes_pls_golite062009
pyrophosphatase activity 0.455976987338331 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.422944846459286 bayes_pls_golite062009
snRNA binding 0.418985924846052 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.338958888186454 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
translation release factor activity 0.178286731022211 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.151650064901878 bayes_pls_golite062009
translation termination factor activity 0.151456842619444 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.0740938021136293 bayes_pls_golite062009
RNA polymerase activity 0.0740938021136293 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009
cytoskeletal protein binding 0.0272673919333979 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [812-1023] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPEILRTPVE SIVLQMKNMN IDNIANFPFP TSPGRSRLEK SLKLLSNLGA IDSEGVLTKL  60
   61 GEQMSLFPLS PRFSKMLIIG QQHGCLPYVI ALVSALSINQ LFVSKQSLLY DAHDKNSRSE 120
  121 ETDLIDDDEI KQKEEYKNRM RGYFNAISRF QAIDPDAPAL SLLSAVCAYD YASDKRKFCK 180
  181 ENYLREKALE EVTNLRKQII GLLKRYMVRV EK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.154902
Match: 2p6rA
Description: No description for 2p6rA was found.

Predicted functions:

Term Confidence Notes
6.55929165712784 bayes_pls_golite062009
RNA-dependent ATPase activity 3.40791872038512 bayes_pls_golite062009
ATP-dependent RNA helicase activity 3.40070584403887 bayes_pls_golite062009
RNA helicase activity 3.25446655280881 bayes_pls_golite062009
helicase activity 1.87693598354249 bayes_pls_golite062009
ATP-dependent helicase activity 1.87127651162653 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.87127651162653 bayes_pls_golite062009
binding 1.77110118899161 bayes_pls_golite062009
nucleic acid binding 1.19966274672886 bayes_pls_golite062009
catalytic activity 0.740488970089403 bayes_pls_golite062009
protein binding 0.345215015803321 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [1024-1183] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFFKLQLKPP TSVQIKALRQ FIASAYIDQV ALYDKEKRGY VTLFPSGSEV VQFVPDRTYN  60
   61 IDSEYVVYLS LHESRSGRVY MSPLTEISPE HLARLAKNTT LLSYSKPLSY PPIRYLDNAT 120
  121 KRECWVIPIL SANIGTGSPS WNLPAVQIIQ KRINGRWVNC

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 16.21467
Match: PF07717.7
Description: No description for PF07717.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle