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View Structure Prediction Details

Protein: SPAC15A10.06
Organism: Schizosaccharomyces pombe
Length: 569 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC15A10.06.

Description E-value Query
Range
Subject
Range
gi|32450774 - gi|32450774|gb|AAM63432.1| Na+/H+ exchanger [Aedes aegypti]
303.0 [0..13] [562..229]
gi|118791508, gi... - gi|118791508|ref|XP_552951.2| AGAP009036-PA [Anopheles gambiae str. PEST], gi|116117635|gb|EAL39028....
AGAP009036-PA - solute carrier family 9 (sodium/hydrogen exchanger), member 3|protein_coding|3R:24426421:24457340:1|...
302.0 [0..23] [562..235]
gi|37727744 - gi|37727744|gb|AAO34131.1| alkali metal ion/proton exchanger 3 [Anopheles gambiae]
297.0 [0..23] [562..235]
Nhe2-PB, Nhe2-PA - The gene Na<sup>+</sup>/H<sup>+</sup> hydrogen exchanger 2 is referred to in FlyBase by the symbol D...
283.0 [0..37] [562..198]
gi|125987481, gi... - gi|54645835|gb|EAL34573.1| GA21648-PA [Drosophila pseudoobscura], gi|125987481|ref|XP_001357503.1| G...
280.0 [0..14] [562..172]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDSKHWVIL LFRRDGDDDD DDGQDPALQE LYSSWALFIL LVLLIGALLT SYYVQSKKIR  60
   61 AIHETVISVF VGMVVGLIIR VSPGLIIQNM VSFHSTYFFN VLLPPIILNS GYELHQSNFF 120
  121 RNIGTILTFA FAGTFISAVT LGVLVYIFSF LNFE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLSMTFVEAL SMGATLSATD PVTVLAIFNS YKVDQKLYTI IFGESILNDA VAIVMFETLQ  60
   61 QFQGKTLHFF TLFSGIGIFI ITFFISLLIG VSIGLITALL LKYSYLRRYP SIESCIILLM 120
  121 AYTSYFFSNG CHMSGVVSLL FCGITLKHYA FF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [307-569]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMSYKAKLST KYVFRVLAQL SENFIFIYLG MSLFTQVDLV YKPIFILITT VAVTASRYMN  60
   61 VFPLSNLLNK FHRQRNGNLI DHIPYSYQMM LFWAGLRGAV GVALAAGFEG ENAQTLRATT 120
  121 LVVVVLTLII FGGTTARMLE ILHIETGVAA DVDSDTEIGM LPWQQSPEFD LENSAMELSD 180
  181 ASAEPVVVDQ QFTTEHFDEG NIAPTLSKKV SSTFEQYQRA AGAFNQFFHS SRDDQAQWLT 240
  241 RFDEEVIKPV LLERDNLKNG TKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.30103
Match: 1lnqA
Description: Potassium channel-related protein MthK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
potassium channel activity 7.45561375804942 bayes_pls_golite062009
voltage-gated potassium channel activity 7.44058571110681 bayes_pls_golite062009
voltage-gated cation channel activity 7.3386698127529 bayes_pls_golite062009
voltage-gated ion channel activity 7.16469552587678 bayes_pls_golite062009
voltage-gated channel activity 7.14063840809955 bayes_pls_golite062009
metal ion transmembrane transporter activity 5.93188092092616 bayes_pls_golite062009
cation channel activity 5.49362429102263 bayes_pls_golite062009
cation transmembrane transporter activity 5.13805155650973 bayes_pls_golite062009
inward rectifier potassium channel activity 5.0997110076666 bayes_pls_golite062009
ion transmembrane transporter activity 5.04374327766634 bayes_pls_golite062009
ion channel activity 4.88752793243149 bayes_pls_golite062009
gated channel activity 4.87650815860853 bayes_pls_golite062009
substrate-specific channel activity 4.76774891791883 bayes_pls_golite062009
passive transmembrane transporter activity 4.7460548761362 bayes_pls_golite062009
channel activity 4.7460548761362 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.64120459994573 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 2.96809690970616 bayes_pls_golite062009
ligand-gated ion channel activity 2.94075163359893 bayes_pls_golite062009
ligand-gated channel activity 2.94075163359893 bayes_pls_golite062009
transporter activity 2.93091397928047 bayes_pls_golite062009
transmembrane transporter activity 2.82224868778929 bayes_pls_golite062009
substrate-specific transporter activity 2.79688978937497 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.13014428099026 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 1.91774061209278 bayes_pls_golite062009
potassium ion transmembrane transporter activity 1.34449386905866 bayes_pls_golite062009
binding 0.355184540089764 bayes_pls_golite062009
active transmembrane transporter activity 0.239024094835991 bayes_pls_golite062009
molecular transducer activity 0.220014544038474 bayes_pls_golite062009
signal transducer activity 0.220014544038474 bayes_pls_golite062009
catalytic activity 0.130477311009645 bayes_pls_golite062009
receptor activity 0.0665855982136239 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle