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View Structure Prediction Details

Protein: SPAC824.04
Organism: Schizosaccharomyces pombe
Length: 341 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC824.04.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
312.0 [0..1] [338..1280]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
299.0 [0..1] [338..1182]
gi|37523925, gi|... - gi|37523925|ref|NP_927302.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
297.0 [0..1] [338..845]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
295.0 [0..1] [338..1068]
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
294.0 [0..1] [340..949]

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Predicted Domain #1
Region A:
Residues: [1-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIGILSSLK PAQSFRDNSL GSFINSIDYS DSGEYVATTC SADDTVQIYD ALDPKQVHTI  60
   61 TCFETGIEVA RFTHHDHNLL LSTTKGNKDI QYVSIYDNKR ISYFSGHTDI VSSIEVSPIE 120
  121 DQFVSTANDK TLKLWKMNQS SRCLGNLDLP SLGIPAYDPT GLVFAVACHS LSRIFLYDVR 180
  181 NYGSDPFSTF TIDDSRYLSR FSFPPMMPEW KHMEFSNDGK CILLSTRANV HYILDAFSGD 240
  241 VLSRLEDFQE LPFSNNFHGG STTFVPQGNF VIGSADDRTL NVWNLRHTFH HKGKTRPPEH 300
  301 RIVSQSIINP GLVKYNPRYD QLLTAGSQLV FWLPEKYALT S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.30103
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone methyltransferase activity (H3-K4 specific) 4.71992275913384 bayes_pls_golite062009
3.48848918010996 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.25521258308263 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
cytoskeletal protein binding 2.20122168933317 bayes_pls_golite062009
RNA binding 2.1927334052131 bayes_pls_golite062009
nucleic acid binding 1.90457914882449 bayes_pls_golite062009
histone methyltransferase activity 1.85632145559025 bayes_pls_golite062009
snoRNA binding 1.76991421703041 bayes_pls_golite062009
structural molecule activity 1.47448876401574 bayes_pls_golite062009
DNA binding 1.4719281452238 bayes_pls_golite062009
actin binding 1.40054662654509 bayes_pls_golite062009
protein methyltransferase activity 1.35170368882651 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.21305848427711 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
transcription factor activity 0.883016478133271 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.676924760416604 bayes_pls_golite062009
transcription repressor activity 0.658573452658359 bayes_pls_golite062009
DNA-dependent ATPase activity 0.625780732991652 bayes_pls_golite062009
telomerase activity 0.51194134550542 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.426429095658617 bayes_pls_golite062009
kinase activity 0.387572734234845 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
protein kinase activity 0.229242350006544 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.226335610368636 bayes_pls_golite062009
DNA helicase activity 0.220747580531792 bayes_pls_golite062009
ligase activity 0.20682813699621 bayes_pls_golite062009
RNA-directed DNA polymerase activity 0.18203222513175 bayes_pls_golite062009
myosin heavy chain kinase activity 0.144032354192911 bayes_pls_golite062009
transcription corepressor activity 0.0532675540353509 bayes_pls_golite062009
N-methyltransferase activity 0.00335766408304172 bayes_pls_golite062009

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