YRC Public Data Repository - Protein Structure Prediction

Protein:	apc11
Organism:	Schizosaccharomyces pombe
Length:	94 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for apc11.

Description	E-value	Query Range	Subject Range
gi\|116200598, gi... - gi\|88175558\|gb\|EAQ83026.1\| conserved hypothetical protein [Chaetomium globosum CBS 148.51], gi\|11620...	90.0	[0..1]	[91..1]
gi\|159122965 - gi\|159122965\|gb\|EDP48085.1\| anaphase promoting complex subunit Apc11, putative [Aspergillus fumigatu... gi\|66844418, gi\|... - gi\|70982532\|ref\|XP_746794.1\| anaphase promoting complex subunit Apc11 [Aspergillus fumigatus Af293],...	85.0	[0..1]	[86..1]
gi\|111071249, gi... - gi\|169596234\|ref\|XP_001791541.1\| hypothetical protein SNOG_00874 [Phaeosphaeria nodorum SN15], gi\|11...	85.0	[0..1]	[89..1]
gi\|90299721, gi\|... - gi\|90299721\|gb\|EAS29352.1\| hypothetical protein CIMG_08098 [Coccidioides immitis RS], gi\|119178538\|r...	83.0	[0..1]	[81..1]
gi\|113427199, gi... - gi\|113427201\|ref\|XP_001133297.1\| PREDICTED: similar to APC11 anaphase promoting complex subunit 11 i...	83.0	[0..1]	[87..1]
gi\|49651389 - gi\|49651389\|emb\|CAG78328.1\| YALI0F17050p [Yarrowia lipolytica] gi\|49651389, gi\|... - gi\|50556222\|ref\|XP_505519.1\| YALI0F17050p [Yarrowia lipolytica], gi\|49651389\|emb\|CAG78328.1\| unnamed...	82.0	[0..1]	[81..1]
gi\|68397830 - gi\|68397830\|ref\|XP_690611.1\| PREDICTED: similar to Polr1a protein [Danio rerio]	82.0	[0..2]	[92..194]
gi\|38109542, gi\|... - gi\|39957834\|ref\|XP_364360.1\| hypothetical protein MG09205.4 [Magnaporthe grisea 70-15], gb\|EAA55398....	80.0	[0..2]	[92..296]
gi\|109486993, gi... - gi\|109486993\|ref\|XP_001058362.1\| PREDICTED: similar to ring finger protein 149 [Rattus norvegicus], ...	80.0	[0..2]	[92..240]
gi\|76656847 - gi\|76656847\|ref\|XP_871863.1\| PREDICTED: similar to anaphase promoting complex subunit 11 homolog [Bo...	80.0	[0..8]	[85..125]

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Predicted Domain #1

Region A:
Residues: [1-94]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVKILRYHA IANWTWDTPK DDVCGICRVP FDGCCPQCTS PGDNCPIVWG KCKHIFHAHC  60
   61 IQNWLATSGS QGQCPMDRQT FVVADSTNEK SETQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.69897
Match:	1u6gB
Description:	Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquitin-protein ligase activity	10.2497392096259	bayes_pls_golite062009
small conjugating protein ligase activity	10.0460587929138	bayes_pls_golite062009
acid-amino acid ligase activity	8.99384576623969	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	7.6988425139962	bayes_pls_golite062009
ligase activity	3.92677358871643	bayes_pls_golite062009
binding	2.58862749918018	bayes_pls_golite062009
NEDD8 ligase activity	2.41658628840288	bayes_pls_golite062009
protein binding	1.49775478023418	bayes_pls_golite062009
small conjugating protein-specific protease activity	1.2126425713931	bayes_pls_golite062009
ubiquitin-specific protease activity	1.03469202541773	bayes_pls_golite062009
nucleic acid binding	0.708499177773075	bayes_pls_golite062009
transcription regulator activity	0.681643203460463	bayes_pls_golite062009
hydrolase activity	0.52386813728704	bayes_pls_golite062009
cysteine-type peptidase activity	0.50197530717959	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.392372133643049	bayes_pls_golite062009
ubiquitin thiolesterase activity	0.265769062717221	bayes_pls_golite062009
DNA binding	0.227671243150662	bayes_pls_golite062009
catalytic activity	0.14112008370434	bayes_pls_golite062009
enzyme binding	0.104373352314595	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: