YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC20G8.09c
Organism:	Schizosaccharomyces pombe
Length:	1033 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC20G8.09c.

Description	E-value	Query Range	Subject Range
gi\|67515931, gi\|... - gi\|67515931\|ref\|XP_657851.1\| hypothetical protein AN0247.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	1284.0	[0..1]	[1032..1]
NAT10_YEAST - RNA cytidine acetyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAT10 PE=... KRE33 - Essential protein, required for biogenesis of the small ribosomal subunit; heterozygous mutant shows...	1284.0	[0..1]	[1031..1]
gi\|70990862, gi\|... - gi\|70990862\|ref\|XP_750280.1\| nucleolar ATPase Kre33 [Aspergillus fumigatus Af293], gi\|66847912\|gb\|EA...	1277.0	[0..1]	[1032..1]
gi\|169770983 - gi\|169770983\|ref\|XP_001819961.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|238486528, gi... - gi\|238486528\|ref\|XP_002374502.1\| nucleolar ATPase Kre33, putative [Aspergillus flavus NRRL3357], gi\|... gi\|83767820 - gi\|83767820\|dbj\|BAE57959.1\| unnamed protein product [Aspergillus oryzae]	1275.0	[0..1]	[1032..1]
gi\|76636224 - gi\|76636224\|ref\|XP_881707.1\| PREDICTED: similar to N-acetyltransferase-like protein isoform 10 [Bos ...	1267.0	[0..1]	[1033..1]
gi\|12697963 - gi\|12697963\|dbj\|BAB21800.1\| KIAA1709 protein [Homo sapiens]	1263.0	[0..1]	[1032..4]
gi\|109106811, gi... - gi\|109106817\|ref\|XP_001115721.1\| PREDICTED: N-acetyltransferase-like protein isoform 5 [Macaca mulat...	1260.0	[0..1]	[1031..1]

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Predicted Domain #1

Region A:
Residues: [1-92]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKKALDSRI PTLIKNGCQE KQRSFFVVVG DRARDQVVNL HWLLSQSKVA ARPNVLWMYK  60
   61 KDLLGFTSHR KKRENKIKKE IKRGIRDPNS ED

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.527	d.68.3	SirA-like
View	Download	0.513	c.5.1	MurCD N-terminal domain
View	Download	0.474	c.25.1	Ferredoxin reductase-like, C-terminal NADP-linked domain
View	Download	0.410	c.23.6	Cobalamin (vitamin B12)-binding domain
View	Download	0.403	c.25.1	Ferredoxin reductase-like, C-terminal NADP-linked domain

Predicted Domain #2

Region A:
Residues: [93-222]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFELFCSITN IRYCYYKESE KILGQTYGML VLQDFEALTP NLLARTIETV EGGGIVVLLL  60
   61 HKLNSLKQLY TMSMDIHSRY RTEAHSDVTA RFNERFILSL GNCENCLVID DELNVLPISG 120
  121 GKNVKALPPT

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	60.200659
Match:	PF08351.2
Description:	No description for PF08351.2 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [223-754]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEEDNSTQNS IKELQESLGE DHPAGALVGV TKTLDQARAV LTFVESIVEK SLKGTVSLTA  60
   61 GRGRGKSAAL GLAIAAAIAH GYSNIFITSP SPENLKTLFE FIFKGFDALN YEEHVDYDII 120
  121 QSTNPAYHNA IVRVNIFRDH RQTIQYISPE DSNVLGQAEL VVIDEAAAIP LPLVRKLIGP 180
  181 YLVFMASTIN GYEGTGRSLS LKLLQQLREQ SRIYSGSGNN KSDSQSHISG RTLKEISLDE 240
  241 PIRYAMGDRI ELWLNKLLCL DAASYVSRMA TQGFPHPSEC SLYRVSRDTL FSYHPISEAF 300
  301 LQRMMSLYVA SHYKNSPNDL QLMSDAPAHQ LFVLLPPVDL KNPKLPDPIC VIQLALEGSI 360
  361 SRESIMNSLS RGQRAGGDLI PWLISQQFQD ENFAALGGAR IVRIAVSPEH VKMGYGTRAM 420
  421 QLLHEYFEGK FISASEEFKA VKHSLKRIGD EEIENTALQT EKIHVRDAKT MPPLLLKLSE 480
  481 LQPEPLHYVG VSYGLTPSLQ KFWKREGYCP LYLRQTANDL TGEHTCVMLR VL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.1
Match:	1uaaA
Description:	DEXX box DNA helicase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	2.58352785213483	bayes_pls_golite062009
binding	2.3830857772509	bayes_pls_golite062009
structural molecule activity	1.70306030734033	bayes_pls_golite062009
RNA helicase activity	1.40594009629203	bayes_pls_golite062009
ATP-dependent RNA helicase activity	1.38650114394757	bayes_pls_golite062009
RNA-dependent ATPase activity	1.372924601535	bayes_pls_golite062009
helicase activity	1.17712281740941	bayes_pls_golite062009
ATP-dependent helicase activity	1.12969667337016	bayes_pls_golite062009
purine NTP-dependent helicase activity	1.12969667337016	bayes_pls_golite062009
RNA binding	0.90930722867621	bayes_pls_golite062009
nucleic acid binding	0.61841039337932	bayes_pls_golite062009
	0.506052368661833	bayes_pls_golite062009
DNA binding	0.327221599656875	bayes_pls_golite062009
transcription regulator activity	0.179080000736404	bayes_pls_golite062009
protein binding	0.102043618157662	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.0283323446458181	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [755-1033]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGRDSEWLGA FAQNFYRRFL SLLGYQFREF AAITALSVLD ACNNGTKYVV NSTSKLTNEE  60
   61 INNVFESYDL KRLESYSNNL LDYHVIVDLL PKLAHLYFSG KFPDSVKLSP VQQSVLLALG 120
  121 LQYKTIDTLE KEFNLPSNQL LAMLVKLSKK IMKCIDEIET KDIEEELGSN KKTESSNSKL 180
  181 PEFTPLQQSL EEELQEGADE AMLALREKQR ELINAIDLEK YAIRGNEEDW KAAENQIQKT 240
  241 NGKGARVVSI KGEKRKNNSL DASDKKTKEK PSSKKKFRK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.39794
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: