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View Structure Prediction Details

Protein: SPAC1F8.04c
Organism: Schizosaccharomyces pombe
Length: 463 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC1F8.04c.

Description E-value Query
Range
Subject
Range
gi|21228381, gi|... - gi|21228381|ref|NP_634303.1| N-ethylammeline chlorohydrolase [Methanosarcina mazei Go1], gi|20906853...
277.0 [0..1] [451..29]
gi|19915122, gi|... - gi|20090140|ref|NP_616215.1| N-ethylammeline chlorohydrolase [Methanosarcina acetivorans C2A], gi|19...
272.0 [0..1] [452..14]
MTAD_THEP3 - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Thermoanaerobacter pseudethanolicus (strai...
MTAD_THEPX - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Thermoanaerobacter sp. (strain X514) GN=mt...
gi|241883707, gi... - gi|241903909|ref|ZP_04788624.1| amidohydrolase [Thermoanaerobacter brockii subsp. finnii Ako-1], gi|...
gi|242230758, gi... - gi|242257720|ref|ZP_04802574.1| amidohydrolase [Thermoanaerobacter sp. X513], gi|242230758|gb|EES331...
265.0 [0..1] [451..3]
gi|47551681, gi|... - gi|47777976|ref|YP_018505.2| chlorohydrolase [Bacillus anthracis str. 'Ames Ancestor'], gi|47551681|...
gi|30256531, gi|... - gi|30261905|ref|NP_844282.1| chlorohydrolase [Bacillus anthracis str. Ames], gi|30256531|gb|AAP25768...
MTAD_BACC0 - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus cereus (strain AH820) GN=mtaD PE=...
MTAD_BACAN - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus anthracis GN=mtaD PE=3 SV=1
gi|196033506, gi... - gi|196033506|ref|ZP_03100918.1| chlorohydrolase family protein [Bacillus cereus W], gi|195993940|gb|...
gi|190562545, gi... - gi|190566410|ref|ZP_03019328.1| chlorohydrolase family protein [Bacillus anthracis Tsiankovskii-I], ...
MTAD_BACAC - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus anthracis (strain CDC 684 / NRRL ...
gi|170707271, gi... - gi|170707271|ref|ZP_02897726.1| chlorohydrolase family protein [Bacillus anthracis str. A0389], gi|1...
gi|170670025, gi... - gi|170686328|ref|ZP_02877550.1| chlorohydrolase family protein [Bacillus anthracis str. A0465], gi|1...
gi|167531505, gi... - gi|167633467|ref|ZP_02391792.1| chlorohydrolase family protein [Bacillus anthracis str. A0442], gi|1...
gi|165869419, gi... - gi|165869419|ref|ZP_02214078.1| chlorohydrolase family protein [Bacillus anthracis str. A0488], gi|1...
gi|254741168 - gi|254741168|ref|ZP_05198856.1| chlorohydrolase [Bacillus anthracis str. Kruger B]
gi|254723990 - gi|254723990|ref|ZP_05185776.1| chlorohydrolase [Bacillus anthracis str. A1055]
gi|254684463 - gi|254684463|ref|ZP_05148323.1| chlorohydrolase [Bacillus anthracis str. CNEVA-9066]
MTAD_BACAA - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus anthracis (strain A0248) GN=mtaD ...
gi|254759956 - gi|254759956|ref|ZP_05211980.1| chlorohydrolase [Bacillus anthracis str. Australia 94]
gi|254755419 - gi|254755419|ref|ZP_05207453.1| chlorohydrolase [Bacillus anthracis str. Vollum]
gi|49184742, gi|... - gi|49184742|ref|YP_027994.1| chlorohydrolase [Bacillus anthracis str. Sterne], gi|49178669|gb|AAT540...
264.0 [0..5] [450..7]
MTAD_PYRFU - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Pyrococcus furiosus (strain ATCC 43587 / D...
MTAD_PYRFU - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Pyrococcus furiosus GN=mtaD PE=3 SV=1
263.0 [0..1] [446..1]
gi|89156863, gi|... - gi|89205120|ref|ZP_01183692.1| Amidohydrolase:Amidohydrolase-like [Bacillus weihenstephanensis KBAB4...
262.0 [0..1] [450..5]
MTAD_BACCR - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus cereus (strain ATCC 14579 / DSM 3...
261.0 [0..5] [450..7]
MTAD_BACHK - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus thuringiensis subsp. konkukian GN...
MTAD_BACCZ - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus cereus (strain ZK / E33L) GN=mtaD...
MTAD_BACHK - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus thuringiensis subsp. konkukian (s...
261.0 [0..5] [450..7]
DADD_METBF - 5'-deoxyadenosine deaminase OS=Methanosarcina barkeri (strain Fusaro / DSM 804) GN=dadD PE=3 SV=1
261.0 [0..1] [451..4]
gi|83766572 - gi|83766572|dbj|BAE56712.1| unnamed protein product [Aspergillus oryzae]
gi|238497794, gi... - gi|238497794|ref|XP_002380132.1| guanine deaminase, putative [Aspergillus flavus NRRL3357], gi|22069...
gi|169768488 - gi|169768488|ref|XP_001818714.1| hypothetical protein [Aspergillus oryzae RIB40]
260.0 [0..1] [460..1]

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Predicted Domain #1
Region A:
Residues: [1-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLYTHANIIT VNPTRDILID GAILVKDGSN TIDDIGKTDR LVSIYPNEKH KSLEGHIVMP  60
   61 GLISLHVHLA QSLLRSAADD LPLISWLCDT VWKMQGNFTQ EDGYVASQLT IAEMLKSGTT 120
  121 TFVEALFAQR YGIEGAVKAV IESGIRGCIG KVVMDQPRYA TQTGVSMHEG LIENSNSLNQ 180
  181 AVESHSKFHG KGNGRVEIWF GARTPGGVSE ELYRKMVKIA RANNIGITMH CAEVKADREF 240
  241 FASKEHTPMT YCKDLGLLGP KTVLAHMVHL DTQDLEILEK HGNGTSVAHC PVSNSKLGSG 300
  301 IAPLKEMLEK SIIVGIGCDG CPCNNTMDLL QEMKMASLLP KALHGDPSIV PAEKIVEMAT 360
  361 INGAKALGRD DLGSLEVGKK ADFISLDLSN KLYAQPLRDL VSAVVYIATG ADVATVVIDG 420
  421 KLIVEDHVLL TIDEPKLIDK AKKHGKKLQE RAKVDVKGRW KEI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.0
Match: 1j6pA
Description: Hypothetical protein TM0936; Hypothetical protein TM0936, probable catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
guanine deaminase activity 3.78802420851729 bayes_pls_golite062009
hydrolase activity 3.06979421893431 bayes_pls_golite062009
adenine deaminase activity 1.87830487335945 bayes_pls_golite062009
deaminase activity 1.79186203771221 bayes_pls_golite062009
catalytic activity 1.70199291046899 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.60895003474033 bayes_pls_golite062009
dihydropyrimidinase activity 1.51712244686012 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 0.787370269329878 bayes_pls_golite062009
binding 0.771164376899668 bayes_pls_golite062009
nucleic acid binding 0.629962267754185 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 0.573107361273483 bayes_pls_golite062009
transcription regulator activity 0.506159010274668 bayes_pls_golite062009
DNA binding 0.462348875991261 bayes_pls_golite062009
peptidase activity 0.370872229900721 bayes_pls_golite062009
dihydroorotase activity 0.203044795244555 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle