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View Structure Prediction Details

Protein: ccs1
Organism: Schizosaccharomyces pombe
Length: 297 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ccs1.

Description E-value Query
Range		 Subject
Range
CCS_PIG - Copper chaperone for superoxide dismutase OS=Sus scrofa GN=CCS PE=2 SV=1
 162.0 [0..2] [229..12]
CCS - copper chaperone for superoxide dismutase
 158.0 [0..1] [224..11]
gi|60830005 - gi|60830005|gb|AAX36906.1| copper chaperone for superoxide dismutase [synthetic construct]
 157.0 [0..1] [224..11]
CCS_RAT - Copper chaperone for superoxide dismutase OS=Rattus norvegicus GN=Ccs PE=1 SV=1
 157.0 [0..1] [223..11]
CCS_MOUSE - Copper chaperone for superoxide dismutase OS=Mus musculus GN=Ccs PE=1 SV=1
 155.0 [0..2] [223..12]
gi|57099643 - gi|57099643|ref|XP_533218.1| PREDICTED: similar to Copper chaperone for superoxide dismutase (Supero...
 154.0 [0..2] [229..12]
gi|52139009, gi|... - gi|58332386|ref|NP_001011020.1| copper chaperone for superoxide dismutase [Xenopus (Silurana) tropic...
 150.0 [0..1] [225..10]
gi|109105430 - gi|109105430|ref|XP_001118002.1| PREDICTED: copper chaperone for superoxide dismutase [Macaca mulatt...
 149.0 [0..9] [224..1]
gi|47212233 - gi|47212233|emb|CAF96200.1| unnamed protein product [Tetraodon nigroviridis]
 147.0 [0..3] [226..8]

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Predicted Domain #1
Region A:
Residues: [1-297] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFEVEYLIKD CDDVNKNTLE QEFQDLNIED WKWDAATGQL IVKGSVSPSK VLRRLENATS  60
   61 KPILIRGASN KESGVSILYE ANEDITQIPK VYGLCRFIPT EEKIFLDLIA TQLLPNREYT 120
  121 GLVTISGDIS RGLKSAGDSL VTLFNANSNE QGKIVLDKEV SGSLPNWIGH CFVLKCVDDS 180
  181 DSATMGIISR SAGLGQNTKQ ICACTGKSLW TEHAELKSVN EGSSCCSKKD SSPSEKPSCC 240
  241 SQEKKSCCSS KKPSCCSQEK KGCCSTEKTS CCSQEKKSCC TSEKPSCCSN GKSTVCA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.221849
Match: 1jk9B
Description: Copper chaperone for superoxide dismutase, C-terminal domain; Copper chaperone for superoxide dismutase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
copper-exporting ATPase activity 5.04749761961029 bayes_pls_golite062009
copper-transporting ATPase activity 5.03252922496602 bayes_pls_golite062009
copper-dependent protein binding 4.95395467138629 bayes_pls_golite062009
copper ion binding 4.91808158964828 bayes_pls_golite062009
protein phosphatase 2B binding 3.97076340458771 bayes_pls_golite062009
superoxide dismutase activity 3.77011290735355 bayes_pls_golite062009
oxidoreductase activity, acting on superoxide radicals as acceptor 3.77011290735355 bayes_pls_golite062009
copper chaperone activity 3.53752588768671 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 3.27250923701445 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 2.98847682261773 bayes_pls_golite062009
metallochaperone activity 2.82622922333955 bayes_pls_golite062009
copper ion transmembrane transporter activity 2.53311528765098 bayes_pls_golite062009
superoxide dismutase copper chaperone activity 2.52817596471383 bayes_pls_golite062009
ion transmembrane transporter activity 2.46331862428318 bayes_pls_golite062009
cation transmembrane transporter activity 2.41954384727602 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.30916666149383 bayes_pls_golite062009
binding 2.28211284921339 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.0278666635337 bayes_pls_golite062009
transition metal ion binding 1.81903588647517 bayes_pls_golite062009
metal ion binding 1.79413011653575 bayes_pls_golite062009
cation binding 1.79413011653575 bayes_pls_golite062009
ion binding 1.78699219376941 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 1.64083855886256 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.63756992236587 bayes_pls_golite062009
active transmembrane transporter activity 1.53883152283038 bayes_pls_golite062009
primary active transmembrane transporter activity 1.39970933331095 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 1.39813577306223 bayes_pls_golite062009
cation-transporting ATPase activity 1.38250427863906 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 1.38072038370649 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 1.38072038370649 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 1.37826353967694 bayes_pls_golite062009
transporter activity 1.33910763967058 bayes_pls_golite062009
transmembrane transporter activity 1.12504351752996 bayes_pls_golite062009
catalytic activity 1.09233965765942 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.964982981309176 bayes_pls_golite062009
ATPase activity 0.948107394178372 bayes_pls_golite062009
hydrolase activity 0.930068054146566 bayes_pls_golite062009
protein binding 0.916153188966515 bayes_pls_golite062009
pyrophosphatase activity 0.903757171463128 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.887068390699274 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.884791447137788 bayes_pls_golite062009
ATPase activity, coupled 0.835595471295029 bayes_pls_golite062009
phosphatase binding 0.761846411630881 bayes_pls_golite062009
protein phosphatase binding 0.76170223416265 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.704985452118462 bayes_pls_golite062009
substrate-specific transporter activity 0.618042428454534 bayes_pls_golite062009
enzyme binding 0.53808149901487 bayes_pls_golite062009
chaperone binding 0.468633271737412 bayes_pls_golite062009
zinc ion binding 0.25600715352161 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
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