YRC Public Data Repository - Protein Structure Prediction

Protein:	phx1
Organism:	Schizosaccharomyces pombe
Length:	942 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for phx1.

Description	E-value	Query Range	Subject Range
gi\|170946443, gi... - gi\|170946443\|emb\|CAP73244.1\| unnamed protein product [Podospora anserina], gi\|11322493\|emb\|CAC16792.... gi\|171692989 - gi\|171692989\|ref\|XP_001911419.1\| unnamed protein product [Podospora anserina]	354.0	[0..413]	[846..166]
gi\|39940774, gi\|... - gi\|39940774\|ref\|XP_359924.1\| hypothetical protein MG04853.4 [Magnaporthe grisea 70-15], gb\|EAA52161....	341.0	[0..408]	[846..188]
gi\|116198845, gi... - gi\|88178857\|gb\|EAQ86325.1\| hypothetical protein CHGG_07578 [Chaetomium globosum CBS 148.51], gi\|1161...	335.0	[0..416]	[846..187]
gi\|85102414 - gi\|85102414\|ref\|XP_961320.1\| hypothetical protein NCU03593 [Neurospora crassa OR74A] gi\|28922864, gi\|... - gi\|38566786\|emb\|CAE76096.1\| probable homeoprotein [Neurospora crassa], gi\|32404564\|ref\|XP_322895.1\| ...	333.0	[0..417]	[846..178]
gi\|42553461, gi\|... - gi\|46132980\|ref\|XP_389195.1\| hypothetical protein FG09019.1 [Gibberella zeae PH-1], gi\|42553461\|gb\|E...	332.0	[0..421]	[823..173]
gi\|40745685, gi\|... - gi\|67523105\|ref\|XP_659613.1\| hypothetical protein AN2009.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	322.0	[0..415]	[844..66]
gi\|27450537 - gi\|27450537\|gb\|AAO14630.1\|AF467710_1 RfeB [Emericella nidulans]	319.0	[0..415]	[844..60]
gi\|70993914, gi\|... - gi\|70993914\|ref\|XP_751804.1\| homeobox transcription factor (RfeB), putative [Aspergillus fumigatus A...	281.0	[0..415]	[888..229]
gi\|83768142 - gi\|83768142\|dbj\|BAE58281.1\| unnamed protein product [Aspergillus oryzae] gi\|169771627 - gi\|169771627\|ref\|XP_001820283.1\| hypothetical protein [Aspergillus oryzae RIB40]	260.0	[0..415]	[861..158]
gi\|115492331, gi... - gi\|115492331\|ref\|XP_001210793.1\| hypothetical protein ATEG_00707 [Aspergillus terreus NIH2624], gi\|1...	252.0	[0..415]	[851..157]

Back

Predicted Domain #1

Region A:
Residues: [1-139]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSYSNPENG GQINDNINYS EKRPTMLPEN LSLSNYDMDS FLGQFPSDNN MQLPHSTYEQ  60
   61 HLQGEQQNPT NPNYFPPEFD ENKVDWKQEK PKPDAPSFAD NNSFDNVNSS KLTNPSPVQP 120
  121 NIVKSESEPA NSKQNEVVE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [140-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATSVEKAKEN VAHESGTPES GGSTSAPKSK KQRLTADQLA YLLREFSKDT NPPPAIREKI  60
   61 GRELNIPERS VTIWFQNRRA KSKLISRRQE EERQRILR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.0
Match:	1b72A
Description:	Homeobox protein hox-b1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	5.13863038737912	bayes_pls_golite062009
DNA binding	4.66369707598026	bayes_pls_golite062009
nucleic acid binding	4.51452285155271	bayes_pls_golite062009
transcription factor activity	4.06706589695599	bayes_pls_golite062009
binding	3.02779747447702	bayes_pls_golite062009
sequence-specific DNA binding	2.41271657675151	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.26183812259792	bayes_pls_golite062009
transcription repressor activity	1.91962622287073	bayes_pls_golite062009
transcription activator activity	1.77700860354597	bayes_pls_golite062009
transcription factor binding	1.40653841901929	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.14886080629275	bayes_pls_golite062009
chromatin binding	1.04132983826241	bayes_pls_golite062009
transcription cofactor activity	0.84983974758882	bayes_pls_golite062009
protein binding	0.830419844171551	bayes_pls_golite062009
transcription corepressor activity	0.25931464844298	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [238-429]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQRELDSLNQ KVSQAFAHEV LSTSPTSPYV GGIAANRQYA NTLLPKPTRK TGNFYMKSGP  60
   61 MQSSMEPCIA ESDIPIRQSL SSTYYNSLSP NAVPVSSQRK YSASSYSAIP NAMSVSNQAF 120
  121 DVESPPSSYA TPLTGIRMPQ PESDLYSYPR EVSPSSGGYR MFGHSKPSSY KASGPVRPPN 180
  181 MATGHMRTSS EP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [430-603]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSYDSEFYYF SCTLLVIGLW KRLRASPQDL MCFYSPPKKL FAYLIQFQGI QYRIEYSFFV  60
   61 IESIHVFRVE EPLLNELSAT ASSRDKPAPN EYWLQMDIQL SVPPVFHMIT SEGQGNCTDF 120
  121 TEGNQASEVL LHSLMGRATS MFQMLDRVRR ASPELGSVIR LQKGLNPHQF LDPQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [604-847]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WANQLPRQPD SSVFDHQGRN PPIQGLSHDT SSEYGNKSQF KRLRSTSTPA RQDLAQHLLP  60
   61 PKTNTEGLMH AQSVSPITQA MKSANVLEGS STRLNSYEPS VSSAYPHHNL ALNLDNTQFG 120
  121 ELGTSNISYP LSAPSDVGSL PRASNSPSRP VMHPNTQGIN TEIKDMAAQF PNSQTGGLTP 180
  181 NSWSMNTNVS VPFTTQNREF GGIGSSSIST TMNAPSQQLS QVPFGDVSLA TENSVPSYGF 240
  241 EVPS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [848-942]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EESVYAQART NSSVSAGVAP RLFIQTPSIP LASSAGQDSN LIEKSSSGGV YASQPGASGY  60
   61 LSHDQSGSPF EDVYSPSAGI DFQKLRGQQF SPDMQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.250	a.74.1	Cyclin-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: