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View Structure Prediction Details

Protein: SPAC1D4.09c
Organism: Schizosaccharomyces pombe
Length: 240 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC1D4.09c.

Description E-value Query
Range
Subject
Range
gi|148236615, gi... - gi|32484231|gb|AAH54212.1| MGC64388 protein [Xenopus laevis], gi|148236615|ref|NP_001082703.1| hypot...
205.0 [0..1] [231..1]
gi|45768830, gi|... - gi|47575820|ref|NP_001001254.1| hypothetical protein LOC407963 [Xenopus (Silurana) tropicalis], gi|4...
204.0 [0..1] [218..1]
RTF2_RAT - Protein RTF2 homolog OS=Rattus norvegicus GN=Rtfdc1 PE=2 SV=1
203.0 [0..1] [215..1]
gi|109091530 - gi|109091530|ref|XP_001090175.1| PREDICTED: hypothetical protein LOC51507 isoform 2 [Macaca mulatta]
203.0 [0..1] [215..1]
C20orf43 - chromosome 20 open reading frame 43
203.0 [0..1] [227..1]
RTF2_MACFA - Protein RTF2 homolog OS=Macaca fascicularis GN=RTFDC1 PE=2 SV=1
203.0 [0..1] [215..1]
RTF2_BOVIN - Protein RTF2 homolog OS=Bos taurus GN=RTFDC1 PE=2 SV=1
203.0 [0..1] [229..1]
gi|220954630, gi... - gi|220954630|gb|ACL89858.1| CG6443-PA [synthetic construct], gi|220944782|gb|ACL84934.1| CG6443-PA [...
CG6443-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6443 (CG6443, FBgn0032290). It is a protein...
203.0 [0..1] [239..1]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNDGGSLPT RNELVKEPGK VPPLDIDFKR SVKSSQFSQC AITDEPLYPP IVSCGLGKLY  60
   61 NKASILQMLL DRSSVPKSPS HIKSLKDVVQ LQVEL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.23
Match: 1wgmA
Description: Solution structure of the U-box in human ubiquitin conjugation factor E4A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.11628925728357 bayes_pls_golite062009
transcription regulator activity 1.34809367817517 bayes_pls_golite062009
nucleic acid binding 1.29443396975472 bayes_pls_golite062009
DNA binding 0.857401028646596 bayes_pls_golite062009
protein binding 0.789504040348248 bayes_pls_golite062009
small conjugating protein ligase activity 0.610199329263848 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.423647874943815 bayes_pls_golite062009
transcription factor binding 0.315997284960041 bayes_pls_golite062009
catalytic activity 0.168711389690753 bayes_pls_golite062009
transcription factor activity 0.14897188736485 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [96-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDSGKVLWLC PITRHVMSDT YQFAYIVPCG HVFEYSALKQ FGEKMCFQCN QVYEEKDVIP  60
   61 INPNAEQLKT LSKRLLDLAL SEKTHSLNKA SKKSNKNGDK KRKHVSKSNS KHAKHELRTN 120
  121 RMLDGENVKS ETSVTDMERV KRVKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.522879
Match: 1e4uA
Description: Not-4 N-terminal RING finger domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.19426901055464 bayes_pls_golite062009
transcription regulator activity 1.37997261357301 bayes_pls_golite062009
nucleic acid binding 1.30336876036582 bayes_pls_golite062009
small conjugating protein ligase activity 1.00637609953328 bayes_pls_golite062009
protein binding 0.901145726644172 bayes_pls_golite062009
DNA binding 0.853765620233342 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.81824834538312 bayes_pls_golite062009
transcription factor binding 0.44693666623428 bayes_pls_golite062009
acid-amino acid ligase activity 0.302877642467793 bayes_pls_golite062009
ligase activity 0.144761439114831 bayes_pls_golite062009
transcription factor activity 0.142558352745445 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle