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View Structure Prediction Details

Protein: ung1
Organism: Schizosaccharomyces pombe
Length: 322 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ung1.

Description E-value Query
Range
Subject
Range
gi|67900896, gi|... - gi|67900896|ref|XP_680704.1| hypothetical protein AN7435.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
389.0 [0..3] [320..1]
gi|7413912 - gi|7413912|emb|CAB85707.1| uracil-DNA glycosylase precursor [Gadus morhua]
387.0 [0..9] [302..9]
gi|28279160, gi|... - gi|41055778|ref|NP_957268.1| uracil-DNA glycosylase [Danio rerio], gi|28279160|gb|AAH45912.1| Uracil...
386.0 [0..20] [302..12]
gi|45383742, gi|... - gi|45383742|ref|NP_989520.1| uracil-DNA glycosylase [Gallus gallus], gi|24571183|gb|AAN62908.1| urac...
382.0 [0..15] [302..12]
gi|31217396, gi|... - gi|6755941|ref|NP_035807.1| uracil DNA glycosylase [Mus musculus], gi|31217396|gb|AAH52853.1| Ung pr...
382.0 [0..28] [302..21]
UNG_AZOVD - Uracil-DNA glycosylase OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=ung PE=3 SV=1
gi|53611343, gi|... - gi|67153345|ref|ZP_00415090.1| Uracil-DNA glycosylase [Azotobacter vinelandii AvOP], ref|ZP_00090188...
377.0 [0..82] [307..10]
gi|83586768, gi|... - gi|83586768|ref|ZP_00925399.1| COG0692: Uracil DNA glycosylase [Escherichia coli 101-1], gi|19443765...
gi|6435761|pdb|1... - Chain A, Crystal Structure Of Escherichia Coli Uracil Dna Glycosylase And Its Complexes With Uracil ...
gi|6435761 - gi|6435761|pdb|1EUG|A Chain A, Crystal Structure Of Escherichia Coli Uracil Dna Glycosylase And Its ...
gi|251785907, gi... - gi|251785907|ref|YP_003000211.1| hypothetical protein B21_02438 [Escherichia coli BL21], gi|24237818...
gi|253323564, gi... - gi|254289316|ref|YP_003055064.1| uracil-DNA glycosylase [Escherichia coli BL21(DE3)], gi|253978623|g...
gi|253974456, gi... - gi|254162555|ref|YP_003045663.1| uracil-DNA glycosylase [Escherichia coli B str. REL606], gi|2539744...
377.0 [0..83] [308..4]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVLNTTDKR KADDTVNKLD GKLKQPRLDN FFKTNTSSPA LKDTQVLDNK ENNSVSKFNK  60
   61 EKWAENLTPA QRKLLQLEID T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [82-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LESSWFDALK DEFLKPYFLN LKEFLMKEWQ SQRVFPPKED IYSWSHHTPL HKTKVILLGQ  60
   61 DPYHNIGQAH GLCFSVRPGI PCPPSLVNIY KAIKIDYPDF VIPKTGYLVP WADQGILMLN 120
  121 ASLTVRAHQA ASHSGKGWET FTSAVLQVAL NRNRKGLVIL AWGTPAAKRL QGLPLKAHYV 180
  181 LRSVHPSPLS AHRGFFECHH FKKTNEWLEE QYGPEKCINW SAVSEQKAKI KSSELESSST 240
  241 E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 105.0
Match: 1eugA
Description: Uracil-DNA glycosylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA N-glycosylase activity 5.22461096584694 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 4.68115068202636 bayes_pls_golite062009
uracil DNA N-glycosylase activity 4.48822773983461 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 2.66280504021689 bayes_pls_golite062009
single-strand selective uracil DNA N-glycosylase activity 2.14678866447561 bayes_pls_golite062009
hydrolase activity 1.91716804176625 bayes_pls_golite062009
catalytic activity 1.59111295908728 bayes_pls_golite062009
mismatch base pair DNA N-glycosylase activity 1.34999321643757 bayes_pls_golite062009
binding 1.2276262882727 bayes_pls_golite062009
structure-specific DNA binding 1.22310035950527 bayes_pls_golite062009
nucleic acid binding 0.901890891144085 bayes_pls_golite062009
DNA binding 0.850361767185031 bayes_pls_golite062009
transcription regulator activity 0.543168797464517 bayes_pls_golite062009
single-stranded DNA binding 0.48698673207018 bayes_pls_golite062009
protein binding 0.272261244770552 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle