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View Structure Prediction Details

Protein: rti1
Organism: Schizosaccharomyces pombe
Length: 371 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rti1.

Description E-value Query
Range
Subject
Range
RAD52 - Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; annea...
356.0 [0..20] [256..53]
RAD22_SCHPO - DNA repair and recombination protein rad22 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN...
rad22 - DNA repair protein Rad22
338.0 [0..5] [261..12]
gi|542221, gi|397583 - pir||S41496 rad22 protein - fission yeast (Schizosaccharomyces pombe), gi|397583|emb|CAA51021.1| rad...
337.0 [0..5] [261..12]
gi|17512302 - gi|17512302|gb|AAH19123.1| Rad52 protein [Mus musculus]
313.0 [0..8] [242..27]
gi|109474108 - gi|109474108|ref|XP_001057419.1| PREDICTED: similar to RAD52 homolog [Rattus norvegicus]
308.0 [0..8] [200..27]
gi|403011 - gi|403011|emb|CAA52978.1| K.lactis Rad52 [Kluyveromyces lactis]
308.0 [0..4] [217..1]
RAD52_KLULA - DNA repair and recombination protein RAD52 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DS...
RAD52_KLULA, RA5... - DNA repair and recombination protein RAD52 OS=Kluyveromyces lactis GN=RAD52 PE=3 SV=2, (P41768) DNA ...
308.0 [0..4] [217..1]

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Predicted Domain #1
Region A:
Residues: [1-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSLPDQSSC EEFTDSQQDK MTKLLAMQLG PEYISRRSGP GGGSVTYLEA WKAIELANEI  60
   61 FGFNGWSSSI QDIHVDYVEE TKEKKFNVGI SVIVRVTLKD GSFHEDVGYG SIENCRVKAL 120
  121 AYEKCKKEGT TDALKRALRN FGSSMGNCLY DKRYIQKILK MAPAQAEFNY DNLLRANKRP 180
  181 YARFAQKVST PIESHANKSV KLEHKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.522879
Match: 1kn0A
Description: The homologous-pairing domain of Rad52 recombinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.14765341131293 bayes_pls_golite062009
nucleic acid binding 3.0351747710117 bayes_pls_golite062009
protein binding 1.64057905923545 bayes_pls_golite062009
RNA binding 1.51047378734681 bayes_pls_golite062009
structural constituent of ribosome 1.43500771925528 bayes_pls_golite062009
DNA binding 1.36164279504822 bayes_pls_golite062009
structural molecule activity 1.28116258970047 bayes_pls_golite062009
transcription regulator activity 1.01871957569312 bayes_pls_golite062009
DNA-dependent ATPase activity 0.904446819959466 bayes_pls_golite062009
structure-specific DNA binding 0.642887555726933 bayes_pls_golite062009
double-stranded RNA binding 0.486416546047936 bayes_pls_golite062009
DNA helicase activity 0.44243422495341 bayes_pls_golite062009
single-stranded DNA binding 0.314856869078672 bayes_pls_golite062009
double-stranded DNA binding 0.26445124843094 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.199046986762565 bayes_pls_golite062009
transcription factor activity 0.1846534408189 bayes_pls_golite062009
DNA strand annealing activity 0.12518470735954 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [207-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIEKKISNVD KPISDLIEND IHESLPALQN PPIQSHSETD LYADEELDSI LMHHERPPIP  60
   61 ESPRVEEFEE LLNQFEGDEK VSVDKIDAHD KMTEAQVVKI PPVQFMNARV AAAENPHIKH 120
  121 EGMAFQLHKK SNSILKSSNI DHNRSMPIRR PSLTSNNSAN TFSTK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle