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View Structure Prediction Details

Protein: tdh1
Organism: Schizosaccharomyces pombe
Length: 336 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tdh1.

Description E-value Query
Range		 Subject
Range
G3P_MOUSE - Glyceraldehyde-3-phosphate dehydrogenase OS=Mus musculus GN=Gapdh PE=1 SV=2
 541.0 [0..3] [335..1]
G3P_RAT - Glyceraldehyde-3-phosphate dehydrogenase OS=Rattus norvegicus GN=Gapdh PE=1 SV=3
 540.0 [0..3] [335..1]
gi|62318276 - gi|62318276|dbj|BAD93764.1| Glyceraldehyde-3-phosphate dehydrogenase [Meriones unguiculatus]
 537.0 [0..3] [335..1]

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Predicted Domain #1
Region A:
Residues: [1-336] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIPKVGING FGRIGRIVLR NALVAKTIQV VAINDPFIDL EYMAYMFKYD STHGRFDGSV  60
   61 EIKDGKLVID GNAIDVHNER DPADIKWSTS GADYVIESTG VFTTQETASA HLKGGAKRVI 120
  121 ISAPSKDAPM YVVGVNEEKF NPSEKVISNA SCTTNCLAPL AKVINDTFGI EEGLMTTVHA 180
  181 TTATQKTVDG PSKKDWRGGR GASANIIPSS TGAAKAVGKV IPALNGKLTG MAFRVPTPDV 240
  241 SVVDLTVKLA KPTNYEDIKA AIKAASEGPM KGVLGYTEDA VVSTDFCGDN HSSIFDASAG 300
  301 IQLSPQFVKL VSWYDNEWGY SRRVVDLVAY TAAKDN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 149.0
Match: 1u8fO
Description: Crystal Structure Of Human Placental Glyceraldehyde-3-Phosphate Dehydrogenase At 1.75 Resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glyceraldehyde-3-phosphate dehydrogenase activity 6.40381118887682 bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity 5.96956214078036 bayes_pls_golite062009
oxidoreductase activity 4.00402564572912 bayes_pls_golite062009
1-deoxy-D-xylulose-5-phosphate reductoisomerase activity 3.16750187025282 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.70673476015931 bayes_pls_golite062009
catalytic activity 2.54843319568228 bayes_pls_golite062009
glucose-6-phosphate dehydrogenase activity 2.2713146106379 bayes_pls_golite062009
inositol-3-phosphate synthase activity 2.2178883592085 bayes_pls_golite062009
transcription regulator activity 1.90939908578582 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1.66955978224275 bayes_pls_golite062009
DNA binding 1.61355789916908 bayes_pls_golite062009
nucleic acid binding 1.48478425318425 bayes_pls_golite062009
hydrolase activity 1.40468563568607 bayes_pls_golite062009
binding 1.22114607236074 bayes_pls_golite062009
retinol dehydrogenase activity 1.16811519855038 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.11682034462164 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.03017667696669 bayes_pls_golite062009
transcription factor activity 0.91090893050278 bayes_pls_golite062009
molecular transducer activity 0.910536752370264 bayes_pls_golite062009
signal transducer activity 0.910536752370264 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 0.88293430762998 bayes_pls_golite062009
NAD or NADH binding 0.74536049628503 bayes_pls_golite062009
intramolecular lyase activity 0.708206800759221 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.527946013169731 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.41382905800454 bayes_pls_golite062009
receptor activity 0.388215697182664 bayes_pls_golite062009
structural molecule activity 0.345975336806588 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 0.331048046502169 bayes_pls_golite062009
collagen binding 0.30621400535957 bayes_pls_golite062009
transmembrane receptor activity 0.211380641599388 bayes_pls_golite062009
NADPH:quinone reductase activity 0.136079082491021 bayes_pls_golite062009
glucose binding 0.13030486887358 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle